AutismKB 2.0

Annotation Details for NEK6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NEK6 ( SID6-1512 )
Gene Full Name: NIMA (never in mitosis gene a)-related kinase 6
Band: 9q33.3
Quick LinksEntrez ID:10783; OMIM: 604884; Uniprot ID:NEK6_HUMAN; ENSEMBL ID: ENSG00000119408; HGNC ID: 7749
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000922IEA-spindle pole-
GO:0005634IDA-nucleus12054534
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm12054534
GO:0005815IDA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005874IEA-microtubule-
GO:0016607IEA-nuclear speck-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding14563848
GO:0004674IDA-protein serine/threonine kinase activity14563848
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0004871IMP-signal transducer activity12761501
GO:0005515IPI-protein binding16476580
GO:0005524IDA-ATP binding14563848
GO:0019894IPI-kinesin binding19001501
GO:0019901IPI-protein kinase binding19001501
GO ID Evidence Qualifier GO_term References
GO:0000910TAS-cytokinesis21200151
GO:0006468IDA-protein phosphorylation12840024
GO:0006915IEA-apoptotic process-
GO:0007059IDA-chromosome segregation14563848
GO:0007077TAS-mitotic nuclear envelope disassembly-
GO:0007165IEA-signal transduction-
GO:0007346TAS-regulation of mitotic cell cycle16280549
GO:0018105IDA-peptidyl-serine phosphorylation19001501
GO:0030071IDA-regulation of mitotic metaphase/anaphase transition14563848
GO:0031572IMP-G2 DNA damage checkpoint18728393
GO:0043123IMP-positive regulation of I-kappaB kinase/NF-kappaB signaling12761501
GO:0046777IDA-protein autophosphorylation14563848
GO:0051225TAS-spindle assembly21200151
GO:2000772TAS-regulation of cellular senescence21200151
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NEK6MCM711034417353931 Affinity Capture-MS
NEK6MCM711600017353931 Affinity Capture-MS
NEK6MYO1C11072517353931 Affinity Capture-MS
NEK6MYO1C11600017353931 Affinity Capture-MS
NEK6PSMD211168117353931 Affinity Capture-MS
NEK6PSMD211600017353931 Affinity Capture-MS
NEK6SLC1A511240117353931 Affinity Capture-MS
NEK6SLC1A511600017353931 Affinity Capture-MS
NEK6USP9X11386717353931 Affinity Capture-MS
NEK6USP9X11600017353931 Affinity Capture-MS
NEK6DYNLL111420617353931 Affinity Capture-MS
NEK6DYNLL111600017353931 Affinity Capture-MS
NEK6SMC311457417353931 Affinity Capture-MS
NEK6SMC311600017353931 Affinity Capture-MS
NEK6NUP9311600017353931 Affinity Capture-MS
NEK6NUP9311504117353931 Affinity Capture-MS
NEK6LRPPRC11543217353931 Affinity Capture-MS
NEK6LRPPRC11600017353931 Affinity Capture-MS
NEK9NEK612487612101123 12840024 17353931 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
NEK9NEK611600012101123 12840024 17353931 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
CCDC85BNEK611619816189514 Two-hybrid
CCDC85BNEK611600016189514 Two-hybrid
NECAB2NEK612003516189514 Two-hybrid
NECAB2NEK611600016189514 Two-hybrid
RUVBL2NEK611606717353931 Affinity Capture-MS
RUVBL2NEK611600017353931 Affinity Capture-MS
KDELR1NEK611614517353931 Affinity Capture-MS
KDELR1NEK611600017353931 Affinity Capture-MS
GCN1L1NEK611618117353931 Affinity Capture-MS
GCN1L1NEK611600017353931 Affinity Capture-MS
CDC37NEK611631217353931 Affinity Capture-MS
CDC37NEK611600017353931 Affinity Capture-MS
NEK7NEK612663617353931 Affinity Capture-MS
NEK7NEK611600017353931 Affinity Capture-MS
EML2NEK611729017353931 Affinity Capture-MS
EML2NEK611600017353931 Affinity Capture-MS
EML3NEK612916117353931 Affinity Capture-MS
EML3NEK611600017353931 Affinity Capture-MS
EML4NEK611816917353931 Affinity Capture-MS
EML4NEK611600017353931 Affinity Capture-MS
PTPLAD1NEK611957017353931 Affinity Capture-MS
PTPLAD1NEK611600017353931 Affinity Capture-MS
FANCINEK612051117353931 Affinity Capture-MS
FANCINEK611600017353931 Affinity Capture-MS
PCID2NEK611600017353931 Affinity Capture-MS
PCID2NEK612090817353931 Affinity Capture-MS
XPO5NEK611600017353931 Affinity Capture-MS
XPO5NEK612157417353931 Affinity Capture-MS
KIAA1967NEK612177517353931 Affinity Capture-MS
KIAA1967NEK611600017353931 Affinity Capture-MS
IPO4NEK612282817353931 Affinity Capture-MS
IPO4NEK611600017353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1891638
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040724-133'