AutismKB 2.0

Annotation Details for NCKAP1


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Basic Information Top
Gene Symbol:NCKAP1 ( FLJ11291,HEM2,KIAA0587,MGC8981,NAP1,NAP125 )
Gene Full Name: NCK-associated protein 1
Band: 2q32.1
Quick LinksEntrez ID:10787; OMIM: 604891; Uniprot ID:NCKP1_HUMAN; ENSEMBL ID: ENSG00000061676; HGNC ID: 7666
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726ISS-ruffle-
GO:0005829TAS-cytosol-
GO:0005925IDA-focal adhesion21423176
GO:0016021IEA-integral component of membrane-
GO:0030027ISS-lamellipodium-
GO:0031209IDA-SCAR complex21107423
GO:0031258IEA-lamellipodium membrane-
GO:0031941ISS-filamentous actin-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11418237
GO:0032403IDA-protein complex binding18560548
GO:0048365IDAcontributes_toRac GTPase binding21107423
GO ID Evidence Qualifier GO_term References
GO:0006915TAS-apoptotic process10673335
GO:0007417TAS-central nervous system development10673335
GO:0010592IMP-positive regulation of lamellipodium assembly18560548
GO:0010592ISS-positive regulation of lamellipodium assembly-
GO:0016032IEA-viral process-
GO:0016601IDA-Rac protein signal transduction21107423
GO:0030838ISS-positive regulation of actin filament polymerization-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:2000601IDA-positive regulation of Arp2/3 complex-mediated actin nucleation21107423
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCKAP1RAC11118179148763 Affinity Capture-Western; Reconstituted Complex
NCKAP1RAC11160039148763 Affinity Capture-Western; Reconstituted Complex
NCKAP1YWHAB11336117353931 Affinity Capture-MS
NCKAP1YWHAB11600317353931 Affinity Capture-MS
NCKAP1YWHAZ11336617353931 Affinity Capture-MS
NCKAP1YWHAZ11600317353931 Affinity Capture-MS
NCKAP1GAS711409416055720 Affinity Capture-MS
NCKAP1GAS711600316055720 Affinity Capture-MS
NCKAP1ABI111532411418237 Affinity Capture-Western; Two-hybrid
NCKAP1ABI111600311418237 Affinity Capture-Western; Two-hybrid
DNMBPNCKAP111600314506234 Affinity Capture-MS
DNMBPNCKAP111686914506234 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1355333
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-4426'