AutismKB 2.0

Annotation Details for IQGAP2


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Basic Information Top
Gene Symbol:IQGAP2 ( - )
Gene Full Name: IQ motif containing GTPase activating protein 2
Band: 5q13.3
Quick LinksEntrez ID:10788; OMIM: 605401; Uniprot ID:IQGA2_HUMAN; ENSEMBL ID: ENSG00000145703; HGNC ID: 6111
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm12515716
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005902IEA-microvillus-
GO:0009986IDA-cell surface12515716
GO:0015629TAS-actin cytoskeleton8756646
GO:0030027IDA-lamellipodium12515716
GO:0030175IDA-filopodium12515716
GO:0030667TAS-secretory granule membrane-
GO:0031941IDAcolocalizes_withfilamentous actin12515716
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003779TAS-actin binding8756646
GO:0005095TAS-GTPase inhibitor activity8756646
GO:0005516IEA-calmodulin binding-
GO:0005547IDA-phosphatidylinositol-3,4,5-trisphosphate binding22493426
GO:0017048IDA-Rho GTPase binding12515716
GO:0048365IDA-Rac GTPase binding12515716
GO:0051015IDA-actin filament binding12515716
GO:0071933IDA-Arp2/3 complex binding12515716
GO ID Evidence Qualifier GO_term References
GO:0007165TAS-signal transduction8756646
GO:0034260IEA-negative regulation of GTPase activity-
GO:0034314IDA-Arp2/3 complex-mediated actin nucleation12515716
GO:0043312TAS-neutrophil degranulation-
GO:0070493IDA-thrombin-activated receptor signaling pathway12515716
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IQGAP2RHOG10688412376551 Reconstituted Complex
IQGAP2RHOG11600412376551 Reconstituted Complex
IQGAP2CDC421160048756646 Affinity Capture-Western; Reconstituted Complex
IQGAP2CDC421074338756646 Affinity Capture-Western; Reconstituted Complex
IQGAP2RAC11118178756646 Affinity Capture-Western; Reconstituted Complex
IQGAP2RAC11160048756646 Affinity Capture-Western; Reconstituted Complex
IQGAP2RELA11190214743216 Affinity Capture-MS
IQGAP2RELA11600414743216 Affinity Capture-MS
IQGAP2UBAC111569117353931 Affinity Capture-MS
IQGAP2UBAC111600417353931 Affinity Capture-MS
IQGAP2CAMKK211588920562859 Affinity Capture-MS
IQGAP2CAMKK211600420562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2449975
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2878'