AutismKB 2.0

Annotation Details for ZNF268


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Basic Information Top
Gene Symbol:ZNF268 ( HZF3,MGC126498 )
Gene Full Name: zinc finger protein 268
Band: 12q24.33
Quick LinksEntrez ID:10795; OMIM: 604753; Uniprot ID:ZN268_HUMAN; ENSEMBL ID: ENSG00000090612; HGNC ID: 13061
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12822888
GO:0005634NAS-nucleus11311945
GO:0005737IDA-cytoplasm15547661
GO:0005829IDA-cytosol-
GO:0015629IDA-actin cytoskeleton-
GO ID Evidence Qualifier GO_term References
GO:0003677NAS-DNA binding11311945
GO:0003700IBA-transcription factor activity, sequence-specific DNA binding-
GO:0003700NAS-transcription factor activity, sequence-specific DNA binding11311945
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter12822888
GO:0006351IEA-transcription, DNA-templated-
GO:0006355NAS-regulation of transcription, DNA-templated11311945
GO:0007346IMP-regulation of mitotic cell cycle23946776
GO:0008284IMP-positive regulation of cell proliferation23091055
GO:0008285IMP-negative regulation of cell proliferation22235304
GO:0030154IEA-cell differentiation-
GO:0030335IMP-positive regulation of cell migration23946776
GO:0043065IMP-positive regulation of apoptotic process22235304
GO:0043066IMP-negative regulation of apoptotic process23091055
GO:0045597IMP-positive regulation of cell differentiation22235304
GO:0046022IMP-positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle23091055
GO:0071157IMP-negative regulation of cell cycle arrest23091055
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99173
  • Data Attributes: HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018