AutismKB 2.0

Annotation Details for ADCY2


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Basic Information Top
Gene Symbol:ADCY2 ( AC2,FLJ16822,FLJ45092,HBAC2,KIAA1060,MGC133314 )
Gene Full Name: adenylate cyclase 2 (brain)
Band: 5p15.31
Quick LinksEntrez ID:108; OMIM: 103071; Uniprot ID:ADCY2_HUMAN; ENSEMBL ID: ENSG00000078295; HGNC ID: 233
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622ISS-intracellular-
GO:0005737IDA-cytoplasm11549699
GO:0005886IDA-plasma membrane11549699
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane-
GO:0008074IBA-guanylate cyclase complex, soluble-
GO:0016020ISS-membrane-
GO:0030425ISS-dendrite-
GO:0045121ISS-membrane raft-
GO ID Evidence Qualifier GO_term References
GO:0000287ISS-magnesium ion binding-
GO:0004016IBANOTadenylate cyclase activity-
GO:0004016ISS-adenylate cyclase activity-
GO:0004016NAS-adenylate cyclase activity1427768
GO:0004383IBA-guanylate cyclase activity-
GO:0005524IEA-ATP binding-
GO:0008179ISS-adenylate cyclase binding-
GO:0030145ISS-manganese ion binding-
GO:0046982ISS-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0003091TAS-renal water homeostasis-
GO:0006171ISS-cAMP biosynthetic process-
GO:0006182IBA-cGMP biosynthetic process-
GO:0007165IBA-signal transduction-
GO:0007188ISS-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-
GO:0007189ISS-adenylate cyclase-activating G-protein coupled receptor signaling pathway-
GO:0007189TAS-adenylate cyclase-activating G-protein coupled receptor signaling pathway-
GO:0007190TAS-activation of adenylate cyclase activity-
GO:0007193TAS-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-
GO:0019933ISS-cAMP-mediated signaling-
GO:0034199TAS-activation of protein kinase A activity-
GO:0071377TAS-cellular response to glucagon stimulus-
GO:1904322ISS-cellular response to forskolin-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ADCY5ADCY21066249268375 Co-fractionation
ADCY5ADCY21066229268375 Co-fractionation
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99676
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060503-69'