Annotation Details for SRCAP

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Basic Information Top

Gene Symbol:	SRCAP ( DOMO1,EAF1,FLJ44499,KIAA0309,SWR1 )
Gene Full Name:	Snf2-related CREBBP activator protein
Band:	16p11.2
Quick Links	Entrez ID:10847; OMIM: 611421; Uniprot ID:SRCAP_HUMAN; ENSEMBL ID: ENSG00000080603; HGNC ID: 16974
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:6 results
Molecular Function:6 results
Biological Process:4 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IDA	-	nucleus	10702287
GO:0005654	IDA	-	nucleoplasm	-
GO:0005794	IDA	-	Golgi apparatus	-
GO:0016604	IDA	-	nuclear body	-
GO:0043234	IDA	-	protein complex	14966270
GO:0048471	IDA	-	perinuclear region of cytoplasm	10702287

GO ID	Evidence	Qualifier	GO_term	References
GO:0003677	IEA	-	DNA binding	-
GO:0003713	TAS	-	transcription coactivator activity	10347196
GO:0004386	IEA	-	helicase activity	-
GO:0004402	TAS	-	histone acetyltransferase activity	10347196
GO:0005515	IPI	-	protein binding	10702287
GO:0005524	IEA	-	ATP binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0006357	TAS	-	regulation of transcription from RNA polymerase II promoter	10347196
GO:0016032	IEA	-	viral process	-
GO:0016573	IEA	-	histone acetylation	-

Protein-Protein Interaction

BioGRID:10 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
SRCAP	CREBBP	116058	10347196 11581372	Affinity Capture-Western; Two-hybrid
SRCAP	CREBBP	107777	10347196 11581372	Affinity Capture-Western; Two-hybrid
SRCAP	EP300	108347	10347196 11581372	Affinity Capture-Western
SRCAP	EP300	116058	10347196 11581372	Affinity Capture-Western
SRCAP	NCOR1	114973	11013263	Co-purification
SRCAP	NCOR1	116058	11013263	Co-purification
SRCAP	CARM1	115760	14500758	Reconstituted Complex; Two-hybrid
SRCAP	CARM1	116058	14500758	Reconstituted Complex; Two-hybrid
RUVBL2	SRCAP	116067	17643375	Affinity Capture-MS
RUVBL2	SRCAP	116058	17643375	Affinity Capture-MS

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:2444036
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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