AutismKB 2.0

Annotation Details for MALT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MALT1 ( DKFZp434L132,MLT,MLT1 )
Gene Full Name: mucosa associated lymphoid tissue lymphoma translocation gene 1
Band: 18q21.32
Quick LinksEntrez ID:10892; OMIM: 604860; Uniprot ID:MALT1_HUMAN; ENSEMBL ID: ENSG00000172175; HGNC ID: 6819
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus16123224
GO:0005730IDA-nucleolus-
GO:0005737IDA-cytoplasm16123224
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0032449NAS-CBM complex15125833
GO:0043234IDA-protein complex15125833
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0002020IEA-protease binding-
GO:0004197NAS-cysteine-type endopeptidase activity11090634
GO:0004842IDA-ubiquitin-protein transferase activity14695475
GO:0004871IMP-signal transducer activity12761501
GO:0005515IPI-protein binding14695475
GO:0008233IDA-peptidase activity18223652
GO:0019209IMPcontributes_tokinase activator activity15125833
GO:0043621IPI-protein self-association15125833
GO ID Evidence Qualifier GO_term References
GO:0001923IEA-B-1 B cell differentiation-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002237IEA-response to molecule of bacterial origin-
GO:0002726IMP-positive regulation of T cell cytokine production15125833
GO:0006508IDA-proteolysis18223652
GO:0006952NAS-defense response10523859
GO:0007250IMP-activation of NF-kappaB-inducing kinase activity15125833
GO:0009620IEA-response to fungus-
GO:0016567IEA-protein ubiquitination-
GO:0031398NAS-positive regulation of protein ubiquitination18223652
GO:0032743IMP-positive regulation of interleukin-2 production15125833
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0042098IEA-T cell proliferation-
GO:0042981IDA-regulation of apoptotic process12819136
GO:0043066NAS-negative regulation of apoptotic process11090634
GO:0043123IMP-positive regulation of I-kappaB kinase/NF-kappaB signaling12761501
GO:0045087IEA-innate immune response-
GO:0050852IDA-T cell receptor signaling pathway15125833
GO:0050852TAS-T cell receptor signaling pathway-
GO:0050856IEA-regulation of T cell receptor signaling pathway-
GO:0050870IC-positive regulation of T cell activation15125833
GO:0051092IMP-positive regulation of NF-kappaB transcription factor activity18223652
GO:0051168IDA-nuclear export16123224
GO:0051259IDA-protein oligomerization15125833
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MALT1TRAF211303815125833 Reconstituted Complex
MALT1TRAF211609815125833 Reconstituted Complex
MALT1TRAF611304115125833 Affinity Capture-Western; Reconstituted Complex
MALT1TRAF611609815125833 Affinity Capture-Western; Reconstituted Complex
MALT1UBE2G211317517353931 Affinity Capture-MS
MALT1UBE2G211609817353931 Affinity Capture-MS
MALT1BCL1011442911090634 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MALT1BCL1011609811090634 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2445027
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020801-2'