Annotation Details for CBX1
Basic Information Top
| Gene Symbol: | CBX1 ( CBX,HP1-BETA,HP1Hs-beta,HP1Hsbeta,M31,MOD1,p25beta ) |
|---|---|
| Gene Full Name: | chromobox homolog 1 |
| Band: | 17q21.32 |
| Quick Links | Entrez ID:10951; OMIM: 604511; Uniprot ID:CBX1_HUMAN; ENSEMBL ID: ENSG00000108468; HGNC ID: 1551 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000775 | IDA | - | chromosome, centromeric region | 8287692 |
| GO:0000784 | IDA | - | nuclear chromosome, telomeric region | 19135898 |
| GO:0000784 | IDA | colocalizes_with | nuclear chromosome, telomeric region | 24270157 |
| GO:0000785 | IDA | - | chromatin | 11101528 |
| GO:0001939 | IEA | - | female pronucleus | - |
| GO:0001940 | IEA | - | male pronucleus | - |
| GO:0005634 | IDA | - | nucleus | 21383955 |
| GO:0005654 | TAS | - | nucleoplasm | 9169582 |
| GO:0005720 | TAS | - | nuclear heterochromatin | 9169582 |
| GO:0005721 | IEA | - | pericentric heterochromatin | - |
| GO:0005819 | IDA | - | spindle | 11101528 |
| GO:0010369 | IEA | - | chromocenter | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003682 | TAS | - | chromatin binding | 9169582 |
| GO:0005515 | IPI | - | protein binding | 9636146 |
| GO:0019899 | IPI | - | enzyme binding | 19486527 |
| GO:0042803 | IEA | - | protein homodimerization activity | - |
| GO:1990226 | IPI | - | histone methyltransferase binding | 19486527 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0045892 | IEA | - | negative regulation of transcription, DNA-templated | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| CBX1 | DNMT1 | 108123 | 12711675 | Reconstituted Complex |
| CBX1 | DNMT1 | 116151 | 12711675 | Reconstituted Complex |
| CBX1 | DNMT3A | 108125 | 12711675 | Reconstituted Complex |
| CBX1 | DNMT3A | 116151 | 12711675 | Reconstituted Complex |
| CBX1 | H3F3A | 109272 | 17403666 | Affinity Capture-MS |
| CBX1 | H3F3A | 116151 | 17403666 | Affinity Capture-MS |
| CBX1 | MYOD1 | 110737 | 20195544 | Affinity Capture-MS |
| CBX1 | MYOD1 | 116151 | 20195544 | Affinity Capture-MS |
| CBX1 | PIM1 | 111310 | 12111331 | Affinity Capture-Western |
| CBX1 | PIM1 | 116151 | 12111331 | Affinity Capture-Western |
| CBX1 | RB1 | 111860 | 12711675 | Reconstituted Complex |
| CBX1 | RB1 | 116151 | 12711675 | Reconstituted Complex |
| CBX1 | RPL12 | 112056 | 16169070 | Two-hybrid |
| CBX1 | RPL12 | 116151 | 16169070 | Two-hybrid |
| CBX1 | SP100 | 112555 | 9636146 | Two-hybrid |
| CBX1 | SP100 | 116151 | 9636146 | Two-hybrid |
| CBX1 | SUV39H1 | 112706 | 10202156 | Affinity Capture-Western; Co-fractionation |
| CBX1 | SUV39H1 | 116151 | 10202156 | Affinity Capture-Western; Co-fractionation |
| CBX1 | UCHL1 | 113192 | 16169070 | Two-hybrid |
| CBX1 | UCHL1 | 116151 | 16169070 | Two-hybrid |
| CBX1 | BAP1 | 113911 | 19615732 | Affinity Capture-MS |
| CBX1 | BAP1 | 116151 | 19615732 | Affinity Capture-MS |
| CBX1 | HIST1H3A | 113946 | 15100215 15136563 15960974 | Affinity Capture-Western; Protein-peptide; Reconstituted Complex |
| CBX1 | HIST1H3A | 116151 | 15100215 15136563 15960974 | Affinity Capture-Western; Protein-peptide; Reconstituted Complex |
| CBX1 | BANF1 | 116151 | 19759913 | Affinity Capture-MS |
| CBX1 | BANF1 | 114342 | 19759913 | Affinity Capture-MS |
| CBX1 | CHD1L | 114929 | 19661379 | Affinity Capture-MS |
| CBX1 | CHD1L | 116151 | 19661379 | Affinity Capture-MS |
| CBX1 | TRIM28 | 115457 | 10330177 11336697 18590578 | Affinity Capture-Western; Reconstituted Complex |
| CBX1 | TRIM28 | 116151 | 10330177 11336697 18590578 | Affinity Capture-Western; Reconstituted Complex |
| CBX1 | EHMT2 | 116123 | 17962312 19706462 | Reconstituted Complex |
| CBX1 | EHMT2 | 116151 | 17962312 19706462 | Reconstituted Complex |
| CBX1 | CBX1 | 116151 | 11336697 16615912 | Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex |
| CBX3 | CBX1 | 116463 | 11336697 | Affinity Capture-Western; Reconstituted Complex |
| CBX3 | CBX1 | 116151 | 11336697 | Affinity Capture-Western; Reconstituted Complex |
| CBX5 | CBX1 | 117030 | 11336697 | Affinity Capture-Western; Reconstituted Complex |
| CBX5 | CBX1 | 116151 | 11336697 | Affinity Capture-Western; Reconstituted Complex |
| ARL5A | CBX1 | 117616 | 12414990 | Two-hybrid |
| ARL5A | CBX1 | 116151 | 12414990 | Two-hybrid |
| C11orf30 | CBX1 | 121270 | 14651845 15947784 16615912 | Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid |
| C11orf30 | CBX1 | 116151 | 14651845 15947784 16615912 | Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid |
| SUV420H2 | CBX1 | 124257 | 15145825 19486527 | Affinity Capture-Western; Reconstituted Complex |
| SUV420H2 | CBX1 | 116151 | 15145825 19486527 | Affinity Capture-Western; Reconstituted Complex |
| C1orf103 | CBX1 | 120905 | 16169070 | Two-hybrid |
| C1orf103 | CBX1 | 116151 | 16169070 | Two-hybrid |
| USP17L2 | CBX1 | 132019 | 19615732 | Affinity Capture-MS |
| USP17L2 | CBX1 | 116151 | 19615732 | Affinity Capture-MS |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| CBX1 | DNMT3B | 193830 | 15120635 | DNMT3B interacts with HP1-beta. This interaction was modeled on a demonstrated interaction between mouse Dnmt3b1 and human HP1-beta. |
| No data |
- MGI ID: MGI:105369
- Data Attributes: MGI curated
- ZFIN ID: ZDB-GENE-030131-4945



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