AutismKB 2.0

Annotation Details for YWHAQ


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Basic Information Top
Gene Symbol:YWHAQ ( 14-3-3,1C5,HS1 )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Band: 2p25.1
Quick LinksEntrez ID:10971; OMIM: 609009; Uniprot ID:1433T_HUMAN; ENSEMBL ID: ENSG00000134308; HGNC ID: 12854
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm15163635
GO:0005739IEA-mitochondrion-
GO:0005829TAS-cytosol-
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane19946888
GO:0030659TAS-cytoplasmic vesicle membrane-
GO:0043234IDA-protein complex22797923
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding7760835
GO:0008022IEA-protein C-terminus binding-
GO:0019904IEA-protein domain specific binding-
GO:0044325IEA-ion channel binding-
GO:0047485IPI-protein N-terminus binding11984006
GO:0071889IEA-14-3-3 protein binding-
GO ID Evidence Qualifier GO_term References
GO:0006605IEA-protein targeting-
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0021762IEP-substantia nigra development22926577
GO:0034766IEA-negative regulation of ion transmembrane transport-
GO:0045892IDA-negative regulation of transcription, DNA-templated15163635
GO:0061024TAS-membrane organization-
GO:1900740TAS-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
YWHAQAR11616811266503 Reconstituted Complex
YWHAQAR10686211266503 Reconstituted Complex
YWHAQBAD1161689369453 15694340 Affinity Capture-Western; Two-hybrid
YWHAQBAD1070489369453 15694340 Affinity Capture-Western; Two-hybrid
YWHAQBAX11616812426317 Affinity Capture-Western; Reconstituted Complex
YWHAQBAX10705712426317 Affinity Capture-Western; Reconstituted Complex
YWHAQBRAF11616817353931 Affinity Capture-MS
YWHAQBRAF10714117353931 Affinity Capture-MS
YWHAQCAMK2A11616818292392 Affinity Capture-Western
YWHAQCAMK2A10726518292392 Affinity Capture-Western
YWHAQCBL1161688663231 11024037 Affinity Capture-Western; Reconstituted Complex
YWHAQCBL1073158663231 11024037 Affinity Capture-Western; Reconstituted Complex
YWHAQCDC25B11616810713667 Reconstituted Complex
YWHAQCDC25B10742910713667 Reconstituted Complex
YWHAQCDKN1B11616812042314 Affinity Capture-Western
YWHAQCDKN1B10746112042314 Affinity Capture-Western
YWHAQLYST11616811984006 Two-hybrid
YWHAQLYST10755211984006 Two-hybrid
YWHAQDAPK111616812911633 Affinity Capture-Western
YWHAQDAPK110798212911633 Affinity Capture-Western
YWHAQDDX611616817353931 Affinity Capture-MS
YWHAQDDX610802217353931 Affinity Capture-MS
YWHAQE2F110820115494392 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQE2F111616815494392 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQEMD11616817620012 Affinity Capture-MS
YWHAQEMD10832517620012 Affinity Capture-MS
YWHAQMARK211616817353931 Affinity Capture-MS
YWHAQMARK210832617353931 Affinity Capture-MS
YWHAQEPB41L210835117353931 Affinity Capture-MS
YWHAQEPB41L211616817353931 Affinity Capture-MS
YWHAQESR111616811266503 Reconstituted Complex
YWHAQESR110840311266503 Reconstituted Complex
YWHAQESR211616811266503 Reconstituted Complex
YWHAQESR210840411266503 Reconstituted Complex
YWHAQING111616816581770 Reconstituted Complex
YWHAQING110983316581770 Reconstituted Complex
YWHAQKIF5B11616817353931 Affinity Capture-MS
YWHAQKIF5B11000017353931 Affinity Capture-MS
YWHAQKIF5C11616817353931 Affinity Capture-MS
YWHAQKIF5C11000117353931 Affinity Capture-MS
YWHAQKRT181100739524113 Affinity Capture-Western
YWHAQKRT181161689524113 Affinity Capture-Western
YWHAQMARK311616817353931 Affinity Capture-MS
YWHAQMARK311031017353931 Affinity Capture-MS
YWHAQMDM211616816943424 Affinity Capture-Western
YWHAQMDM211035816943424 Affinity Capture-Western
YWHAQMEF2D11037311433030 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQMEF2D11616811433030 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
YWHAQMLLT411616817353931 Affinity Capture-MS
YWHAQMLLT411044717353931 Affinity Capture-MS
YWHAQCDK161111549197417 Two-hybrid
YWHAQCDK161161689197417 Two-hybrid
YWHAQPDPK111616812177059 Affinity Capture-Western
YWHAQPDPK111119612177059 Affinity Capture-Western
YWHAQPFKFB211616812853467 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
YWHAQPFKFB211122912853467 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
YWHAQPI4KB11616817353931 Affinity Capture-MS
YWHAQPI4KB11131617353931 Affinity Capture-MS
YWHAQFXYD111616814597563 Reconstituted Complex
YWHAQFXYD111136314597563 Reconstituted Complex
YWHAQMED111616811266503 Reconstituted Complex
YWHAQMED111146511266503 Reconstituted Complex
YWHAQPRKD111616810092600 10831594 Affinity Capture-Western; Reconstituted Complex
YWHAQPRKD111157310092600 10831594 Affinity Capture-Western; Reconstituted Complex
YWHAQPRKCZ11616810620507 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
YWHAQPRKCZ11157610620507 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
YWHAQRAF11161688663231 10620507 10757792 17353931 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
YWHAQRAF11118318663231 10620507 10757792 17353931 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
YWHAQRPL2111616817353931 Affinity Capture-MS
YWHAQRPL2111206417353931 Affinity Capture-MS
YWHAQSRSF111616817353931 Affinity Capture-MS
YWHAQSRSF111232417353931 Affinity Capture-MS
YWHAQSRSF311616817353931 Affinity Capture-MS
YWHAQSRSF311232617353931 Affinity Capture-MS
YWHAQSRSF611616817353931 Affinity Capture-MS
YWHAQSRSF611232917353931 Affinity Capture-MS
YWHAQTERT11616810835362 Reconstituted Complex; Two-hybrid
YWHAQTERT11287410835362 Reconstituted Complex; Two-hybrid
YWHAQTHRA11616811266503 Reconstituted Complex
YWHAQTHRA11292311266503 Reconstituted Complex
YWHAQTSC211616817353931 Affinity Capture-MS
YWHAQTSC211310017353931 Affinity Capture-MS
YWHAQUCP211319810785390 Two-hybrid
YWHAQUCP211616810785390 Two-hybrid
YWHAQUCP311319910785390 Reconstituted Complex; Two-hybrid
YWHAQUCP311616810785390 Reconstituted Complex; Two-hybrid
YWHAQYWHAE11616820936779 Two-hybrid
YWHAQYWHAE11336320936779 Two-hybrid
YWHAQNCOA311616811266503 Reconstituted Complex
YWHAQNCOA311384111266503 Reconstituted Complex
YWHAQNRIP111616811266503 Co-localization; Phenotypic Suppression; Reconstituted Complex
YWHAQNRIP111384311266503 Co-localization; Phenotypic Suppression; Reconstituted Complex
YWHAQPPFIBP111406817353931 Affinity Capture-MS
YWHAQPPFIBP111616817353931 Affinity Capture-MS
YWHAQNCOA111616811266503 Reconstituted Complex
YWHAQNCOA111420011266503 Reconstituted Complex
YWHAQIRS211616817353931 Affinity Capture-MS
YWHAQIRS211420917353931 Affinity Capture-MS
YWHAQUSP811455517353931 Affinity Capture-MS
YWHAQUSP811616817353931 Affinity Capture-MS
YWHAQRABEP111616817353931 Affinity Capture-MS
YWHAQRABEP111458317353931 Affinity Capture-MS
YWHAQARHGEF211616814970201 Affinity Capture-Western
YWHAQARHGEF211461814970201 Affinity Capture-Western
YWHAQTJP211616817353931 Affinity Capture-MS
YWHAQTJP211480917353931 Affinity Capture-MS
YWHAQKIF2311616817353931 Affinity Capture-MS
YWHAQKIF2311487317353931 Affinity Capture-MS
YWHAQHDAC411616811470791 15964851 Affinity Capture-Western; Two-hybrid
YWHAQHDAC411510611470791 15964851 Affinity Capture-Western; Two-hybrid
YWHAQHDAC511616815367659 Affinity Capture-Western; Two-hybrid
YWHAQHDAC511533115367659 Affinity Capture-Western; Two-hybrid
YWHAQDENND4A11555217353931 Affinity Capture-MS
YWHAQDENND4A11616817353931 Affinity Capture-MS
YWHAQPAK411558617353931 Affinity Capture-MS
YWHAQPAK411616817353931 Affinity Capture-MS
YWHAQYAP111616812535517 Affinity Capture-MS
YWHAQYAP111568412535517 Affinity Capture-MS
YWHAQSRSF1011599017353931 Affinity Capture-MS
YWHAQSRSF1011616817353931 Affinity Capture-MS
REM1YWHAQ11878110441394 Far Western
REM1YWHAQ11616810441394 Far Western
CCAR1YWHAQ12086712816952 Affinity Capture-Western
CCAR1YWHAQ11616812816952 Affinity Capture-Western
NIF3L1YWHAQ12192215163635 Affinity Capture-Western
NIF3L1YWHAQ11616815163635 Affinity Capture-Western
CRTC2YWHAQ12830815454081 17353931 Affinity Capture-MS; Affinity Capture-Western
CRTC2YWHAQ11616815454081 17353931 Affinity Capture-MS; Affinity Capture-Western
HDAC7YWHAQ11961316956611 16980613 Affinity Capture-Western; Two-hybrid
HDAC7YWHAQ11616816956611 16980613 Affinity Capture-Western; Two-hybrid
PNKPYWHAQ11644017353931 Affinity Capture-MS
PNKPYWHAQ11616817353931 Affinity Capture-MS
CBWD2YWHAQ12729917353931 Affinity Capture-MS
CBWD2YWHAQ11616817353931 Affinity Capture-MS
EPB41L3YWHAQ11675317353931 Affinity Capture-MS
EPB41L3YWHAQ11616817353931 Affinity Capture-MS
MPRIPYWHAQ11677617353931 Affinity Capture-MS
MPRIPYWHAQ11616817353931 Affinity Capture-MS
C22orf9YWHAQ11690417353931 Affinity Capture-MS
C22orf9YWHAQ11616817353931 Affinity Capture-MS
LARP1YWHAQ11694717353931 Affinity Capture-MS
LARP1YWHAQ11616817353931 Affinity Capture-MS
SH3BP4YWHAQ11719417353931 Affinity Capture-MS
SH3BP4YWHAQ11616817353931 Affinity Capture-MS
EML3YWHAQ12916117353931 Affinity Capture-MS
EML3YWHAQ11616817353931 Affinity Capture-MS
RASGRP3YWHAQ11731517353931 Affinity Capture-MS
RASGRP3YWHAQ11616817353931 Affinity Capture-MS
RAI14YWHAQ11752617353931 Affinity Capture-MS
RAI14YWHAQ11616817353931 Affinity Capture-MS
SUV420H1YWHAQ11930017353931 Affinity Capture-MS
SUV420H1YWHAQ11616817353931 Affinity Capture-MS
LUC7L2YWHAQ11964617353931 Affinity Capture-MS
LUC7L2YWHAQ11616817353931 Affinity Capture-MS
CALML5YWHAQ11973217353931 Affinity Capture-MS
CALML5YWHAQ11616817353931 Affinity Capture-MS
SAMD4BYWHAQ12040717353931 Affinity Capture-MS
SAMD4BYWHAQ11616817353931 Affinity Capture-MS
SPIRE1YWHAQ12123717353931 Affinity Capture-MS
SPIRE1YWHAQ11616817353931 Affinity Capture-MS
PAK6YWHAQ12125117353931 Affinity Capture-MS
PAK6YWHAQ11616817353931 Affinity Capture-MS
KIAA1409YWHAQ12163117353931 Affinity Capture-MS
KIAA1409YWHAQ11616817353931 Affinity Capture-MS
FAM83GYWHAQ56991717353931 Affinity Capture-MS
FAM83GYWHAQ11616817353931 Affinity Capture-MS
KLC2YWHAQ12231317353931 Affinity Capture-MS
KLC2YWHAQ11616817353931 Affinity Capture-MS
PANK2YWHAQ12307917353931 Affinity Capture-MS
PANK2YWHAQ11616817353931 Affinity Capture-MS
EDC3YWHAQ12314417353931 Affinity Capture-MS
EDC3YWHAQ11616817353931 Affinity Capture-MS
KLC4YWHAQ12464817353931 Affinity Capture-MS
KLC4YWHAQ11616817353931 Affinity Capture-MS
HIST2H3CYWHAQ12602518059471 Affinity Capture-Western
HIST2H3CYWHAQ11616818059471 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7135'