AutismKB 2.0

Annotation Details for ADAP1


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Basic Information Top
Gene Symbol:ADAP1 ( CENTA1,GCS1L,p42IP4 )
Gene Full Name: ArfGAP with dual PH domains 1
Band: 7p22.3
Quick LinksEntrez ID:11033; OMIM: 608114; Uniprot ID:ADAP1_HUMAN; ENSEMBL ID: ENSG00000105963,ENSG00000240230; HGNC ID: 16486
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10333475
GO:0005737IDA-cytoplasm10333475
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane10333475
GO ID Evidence Qualifier GO_term References
GO:0005096IDA-GTPase activator activity10333475
GO:0005515IPI-protein binding12893243
GO:0005547IEA-phosphatidylinositol-3,4,5-trisphosphate binding-
GO:0043533TAS-inositol 1,3,4,5 tetrakisphosphate binding12018390
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007166TAS-cell surface receptor signaling pathway10333475
GO:0043087IMP-regulation of GTPase activity10333475
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ADAP1CSNK1A111622211278595 12062430 Affinity Capture-Western; Co-purification; Reconstituted Complex
ADAP1CSNK1A110783611278595 12062430 Affinity Capture-Western; Co-purification; Reconstituted Complex
ADAP1NCL11622212565890 Affinity Capture-Western; Co-purification; Reconstituted Complex
ADAP1NCL11077112565890 Affinity Capture-Western; Co-purification; Reconstituted Complex
ADAP1PIK3CA11622212893243 Biochemical Activity; Reconstituted Complex
ADAP1PIK3CA11130812893243 Biochemical Activity; Reconstituted Complex
ADAP1PRKCE11622212893243 Biochemical Activity
ADAP1PRKCE11156712893243 Biochemical Activity
ADAP1PRKCI11622212893243 Affinity Capture-Western; Reconstituted Complex
ADAP1PRKCI11157012893243 Affinity Capture-Western; Reconstituted Complex
ADAP1PRKD111622212893243 Biochemical Activity; Reconstituted Complex
ADAP1PRKD111157312893243 Biochemical Activity; Reconstituted Complex
ADAP1PRKCZ11622212893243 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
ADAP1PRKCZ11157612893243 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
ADAP1ANP32A11622212565890 Co-purification
ADAP1ANP32A11379112565890 Co-purification
ADAP1PSME311622216169070 Two-hybrid
ADAP1PSME311549216169070 Two-hybrid
No data
Gene Symbol Interactant Interaction ID References Description
ADAP1SUPV3L10549316176273 -
ADAP1SUPV3L10973316176273 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2442201
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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