AutismKB 2.0

Annotation Details for CHD1


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Basic Information Top
Gene Symbol:CHD1 ( DKFZp686E2337 )
Gene Full Name: chromodomain helicase DNA binding protein 1
Band: 5q15-q21.1
Quick LinksEntrez ID:1105; OMIM: 602118; Uniprot ID:CHD1_HUMAN; ENSEMBL ID: ENSG00000153922; HGNC ID: 1915
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus22046413
GO:0005737IDA-cytoplasm22046413
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0004003TAS-ATP-dependent DNA helicase activity9326634
GO:0005515IPI-protein binding22419161
GO:0005524IEA-ATP binding-
GO:0035064IDA-methylated histone binding21029866
GO ID Evidence Qualifier GO_term References
GO:0006338IEA-chromatin remodeling-
GO:0006351IEA-transcription, DNA-templated-
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9326634
GO:0016569IEA-covalent chromatin modification-
GO:0032508IEA-DNA duplex unwinding-
GO:0043923IMP-positive regulation by host of viral transcription25297984
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CHD1ARRB110753017353931 Affinity Capture-MS
CHD1ARRB110690117353931 Affinity Capture-MS
CHD1CEBPA10753018817785 Affinity Capture-Western
CHD1CEBPA10747918817785 Affinity Capture-Western
SSRP1CHD110753010199952 Co-purification
SSRP1CHD111262710199952 Co-purification
HDAC1CHD110753012890497 Affinity Capture-Western
HDAC1CHD110931512890497 Affinity Capture-Western
NCOR1CHD110753012890497 Affinity Capture-Western; Two-hybrid
NCOR1CHD111497312890497 Affinity Capture-Western; Two-hybrid
SAFBCHD111220112890497 Two-hybrid
SAFBCHD110753012890497 Two-hybrid
SRSF3CHD111232612890497 Two-hybrid
SRSF3CHD110753012890497 Two-hybrid
BCLAF1CHD110753012890497 Two-hybrid
BCLAF1CHD111511812890497 Two-hybrid
HIST1H3ACHD110753016372014 Co-crystal Structure
HIST1H3ACHD111394616372014 Co-crystal Structure
HMGA1CHD110753018817785 Affinity Capture-Western
HMGA1CHD110940218817785 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88393
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018