AutismKB 2.0

Annotation Details for ADCY5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ADCY5 ( AC5 )
Gene Full Name: adenylate cyclase 5
Band: 3q21.1
Quick LinksEntrez ID:111; OMIM: 600293; Uniprot ID:ADCY5_HUMAN; ENSEMBL ID: ENSG00000173175; HGNC ID: 236
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IBA-plasma membrane-
GO:0005886ISS-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005929ISS-cilium-
GO:0008074IBA-guanylate cyclase complex, soluble-
GO:0016021IDA-integral component of membrane15385642
GO:0045111IDA-intermediate filament cytoskeleton-
GO ID Evidence Qualifier GO_term References
GO:0004016IDA-adenylate cyclase activity15385642
GO:0004016IMP-adenylate cyclase activity24740569
GO:0004383IBA-guanylate cyclase activity-
GO:0005524IEA-ATP binding-
GO:0008179ISS-adenylate cyclase binding-
GO:0046872IEA-metal ion binding-
GO:0046982ISS-protein heterodimerization activity-
GO:0097110IEA-scaffold protein binding-
GO ID Evidence Qualifier GO_term References
GO:0001973IEA-adenosine receptor signaling pathway-
GO:0003091TAS-renal water homeostasis-
GO:0006171IDA-cAMP biosynthetic process15385642
GO:0006171IMP-cAMP biosynthetic process24740569
GO:0006182IBA-cGMP biosynthetic process-
GO:0007189IMP-adenylate cyclase-activating G-protein coupled receptor signaling pathway24700542
GO:0007189TAS-adenylate cyclase-activating G-protein coupled receptor signaling pathway-
GO:0007190TAS-activation of adenylate cyclase activity-
GO:0007191IEA-adenylate cyclase-activating dopamine receptor signaling pathway-
GO:0007193TAS-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-
GO:0007195IEA-adenylate cyclase-inhibiting dopamine receptor signaling pathway-
GO:0007204IMP-positive regulation of cytosolic calcium ion concentration24740569
GO:0007626IEA-locomotory behavior-
GO:0034199TAS-activation of protein kinase A activity-
GO:0035556IEA-intracellular signal transduction-
GO:0050885IEA-neuromuscular process controlling balance-
GO:0061178IMP-regulation of insulin secretion involved in cellular response to glucose stimulus24740569
GO:0071377TAS-cellular response to glucagon stimulus-
GO:1904322IDA-cellular response to forskolin15385642
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ADCY5ADCY21066249268375 Co-fractionation
ADCY5ADCY21066229268375 Co-fractionation
ADCY5ADCY51066249275169 Two-hybrid
GNAI1ADCY51066249748257 Co-purification
GNAI1ADCY51090329748257 Co-purification
RGS2ADCY510662412604604 Affinity Capture-Western; Reconstituted Complex
RGS2ADCY511192912604604 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99673
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081104-470'