Annotation Details for CIT
Basic Information Top
| Gene Symbol: | CIT ( CRIK,KIAA0949,STK21 ) |
|---|---|
| Gene Full Name: | citron (rho-interacting, serine/threonine kinase 21) |
| Band: | 12q24.23 |
| Quick Links | Entrez ID:11113; OMIM: 605629; Uniprot ID:CTRO_HUMAN; ENSEMBL ID: ENSG00000122966; HGNC ID: 1985 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005829 | TAS | - | cytosol | - |
| GO:0005886 | IEA | - | plasma membrane | - |
| GO:0016020 | IDA | - | membrane | 19946888 |
| GO:0031985 | IEA | - | Golgi cisterna | - |
| GO:0043025 | IEA | - | neuronal cell body | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0004674 | ISS | - | protein serine/threonine kinase activity | 9792683 |
| GO:0005515 | IPI | - | protein binding | 16431929 |
| GO:0005524 | IEA | - | ATP binding | - |
| GO:0017048 | IEA | - | Rho GTPase binding | - |
| GO:0017124 | IEA | - | SH3 domain binding | - |
| GO:0030165 | IDA | - | PDZ domain binding | 17474715 |
| GO:0046872 | IEA | - | metal ion binding | - |
| GO:0097110 | IDA | - | scaffold protein binding | 17474715 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000086 | IEA | - | G2/M transition of mitotic cell cycle | - |
| GO:0000278 | ISS | - | mitotic cell cycle | 11086988 |
| GO:0000281 | IMP | - | mitotic cytokinesis | 27453578 |
| GO:0000910 | IMP | - | cytokinesis | 16236794 |
| GO:0006468 | IEA | - | protein phosphorylation | - |
| GO:0007030 | IEA | - | Golgi organization | - |
| GO:0008064 | IEA | - | regulation of actin polymerization or depolymerization | - |
| GO:0032467 | IMP | - | positive regulation of cytokinesis | 16431929 |
| GO:0035556 | IEA | - | intracellular signal transduction | - |
| GO:0048699 | ISS | - | generation of neurons | 11086988 |
| GO:0051402 | IMP | - | neuron apoptotic process | 27453578 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| CIT | RHOA | 106880 | 8543060 12773565 | Far Western; Reconstituted Complex; Two-hybrid |
| CIT | RHOA | 116290 | 8543060 12773565 | Far Western; Reconstituted Complex; Two-hybrid |
| CIT | RHOB | 106881 | 8543060 | Far Western; Two-hybrid |
| CIT | RHOB | 116290 | 8543060 | Far Western; Two-hybrid |
| CIT | RHOC | 106882 | 8543060 | Two-hybrid |
| CIT | RHOC | 116290 | 8543060 | Two-hybrid |
| CIT | RND3 | 106883 | 12773565 | Two-hybrid |
| CIT | RND3 | 116290 | 12773565 | Two-hybrid |
| CIT | RAC1 | 111817 | 8543060 | Far Western |
| CIT | RAC1 | 116290 | 8543060 | Far Western |
| DISC1 | CIT | 118061 | 12506198 | Two-hybrid |
| DISC1 | CIT | 116290 | 12506198 | Two-hybrid |
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| Gene Symbol | Poly Names | Gene overview in SZGene |
|---|---|---|
| CIT | rs10744743, rs10774517, rs1318272, rs202983, rs203332, rs203340, rs2141835, rs2285595, rs2707736, rs278109, rs278121, rs278124, rs278126, rs2996028, rs3847960, rs440299, rs904655 | Gene overview in SZGene |