AutismKB 2.0

Annotation Details for FAF1


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Basic Information Top
Gene Symbol:FAF1 ( FLJ37524,HFAF1s,UBXD12,UBXN3A,hFAF1 )
Gene Full Name: Fas (TNFRSF6) associated factor 1
Band: 1p32.3
Quick LinksEntrez ID:11124; OMIM: 604460; Uniprot ID:FAF1_HUMAN; ENSEMBL ID: ENSG00000185104; HGNC ID: 3578
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus15596450
GO:0005635IEA-nuclear envelope-
GO:0005829IDA-cytosol15596450
GO:0031265NAS-CD95 death-inducing signaling complex12702723
GO:0034098IDA-VCP-NPL4-UFD1 AAA ATPase complex18775313
GO:0048471IDA-perinuclear region of cytoplasm11713579
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15688372
GO:0019887NAS-protein kinase regulator activity11713579
GO:0019901IDA-protein kinase binding11713579
GO:0019904IEA-protein domain specific binding-
GO:0031072IDA-heat shock protein binding15596450
GO:0031625IDA-ubiquitin protein ligase binding18775313
GO:0043130IDA-ubiquitin binding18775313
GO:0051059IPI-NF-kappaB binding14600157
GO ID Evidence Qualifier GO_term References
GO:0006915IEA-apoptotic process-
GO:0007253IMP-cytoplasmic sequestering of NF-kappaB14600157
GO:0008219IMP-cell death15743842
GO:0010942IDA-positive regulation of cell death15596450
GO:0030155IEA-regulation of cell adhesion-
GO:0031334IMP-positive regulation of protein complex assembly15688372
GO:0042176IMP-regulation of protein catabolic process15743842
GO:0043065NAS-positive regulation of apoptotic process10462485
GO:0043161NAS-proteasome-mediated ubiquitin-dependent protein catabolic process15743842
GO:0045859IEA-regulation of protein kinase activity-
GO:1902043IEA-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FAF1FAS1068518524870 Affinity Capture-Western
FAF1FAS1162988524870 Affinity Capture-Western
FAF1CSNK2B10784310094392 Two-hybrid
FAF1CSNK2B11629810094392 Two-hybrid
FAF1RAE111629819615732 Affinity Capture-MS
FAF1RAE111405419615732 Affinity Capture-MS
FAF1G3BP111544819615732 Affinity Capture-MS
FAF1G3BP111629819615732 Affinity Capture-MS
ASCC2FAF112392116169070 Two-hybrid
ASCC2FAF111629816169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
FAF1rs11587750, rs12568008, rs1398868, rs1416685, rs1948808, rs3862271, rs4313442, rs4347253 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:109419
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2863'