AutismKB 2.0

Annotation Details for CHGA


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Basic Information Top
Gene Symbol:CHGA ( CGA )
Gene Full Name: chromogranin A (parathyroid secretory protein 1)
Band: 14q32.12
Quick LinksEntrez ID:1113; OMIM: 118910; Uniprot ID:CMGA_HUMAN; ENSEMBL ID: ENSG00000100604; HGNC ID: 1929
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615ISS-extracellular space-
GO:0030141ISS-secretory granule-
GO:0030658IEA-transport vesicle membrane-
GO:0042583ISS-chromaffin granule-
GO:0042629IEA-mast cell granule-
GO:0048471IDA-perinuclear region of cytoplasm20862257
No data
GO ID Evidence Qualifier GO_term References
GO:0002026ISS-regulation of the force of heart contraction-
GO:0002551IDA-mast cell chemotaxis21214543
GO:0006996ISS-organelle organization-
GO:0008217TAS-regulation of blood pressure8406464
GO:0019730TAS-antimicrobial humoral response-
GO:0030816ISS-positive regulation of cAMP metabolic process-
GO:0031640IEA-killing of cells of other organism-
GO:0032762IDA-mast cell cytokine production21214543
GO:0033604IDA-negative regulation of catecholamine secretion15326220
GO:0043303IDA-mast cell degranulation21214543
GO:0045087NAS-innate immune response15723172
GO:0045576IDA-mast cell activation21214543
GO:0050829IDA-defense response to Gram-negative bacterium15723172
GO:0050830IDA-defense response to Gram-positive bacterium15723172
GO:0050832IEA-defense response to fungus-
GO:0060452ISS-positive regulation of cardiac muscle contraction-
GO:0086030ISS-adrenergic receptor signaling pathway involved in cardiac muscle relaxation-
GO:0097756ISS-negative regulation of blood vessel diameter-
GO:1900738ISS-positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway-
GO:1901215ISS-negative regulation of neuron death-
GO:1901899ISS-positive regulation of relaxation of cardiac muscle-
GO:2000707ISS-positive regulation of dense core granule biogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLGCHGA10753811342539 Biochemical Activity
PLGCHGA11135611342539 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
CHGArs729940, rs9658635 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88394
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041010-161'