AutismKB 2.0

Annotation Details for PLA2G16


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Basic Information Top
Gene Symbol:PLA2G16 ( AdPLA,H-REV107-1,HRASLS3,HREV107,HREV107-3,MGC118754 )
Gene Full Name: phospholipase A2, group XVI
Band: 11q12.3-q13.1
Quick LinksEntrez ID:11145; OMIM: NA; Uniprot ID:PAG16_HUMAN; ENSEMBL ID: ENSG00000176485; HGNC ID: 17825
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005777ISS-peroxisome-
GO:0005778IEA-peroxisomal membrane-
GO:0005783IEA-endoplasmic reticulum-
GO:0005829TAS-cytosol-
GO:0016021IEA-integral component of membrane-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004623IDA-phospholipase A2 activity19047760
GO:0004623TAS-phospholipase A2 activity-
GO:0005515IPI-protein binding16189514
GO:0008970IDA-phosphatidylcholine 1-acylhydrolase activity19047760
GO:0016746TAS-transferase activity, transferring acyl groups-
GO:0052739IEA-phosphatidylserine 1-acylhydrolase activity-
GO:0052740IEA-1-acyl-2-lysophosphatidylserine acylhydrolase activity-
GO ID Evidence Qualifier GO_term References
GO:0006641ISS-triglyceride metabolic process-
GO:0006644IDA-phospholipid metabolic process20100577
GO:0007031ISS-peroxisome organization-
GO:0008654IEA-phospholipid biosynthetic process-
GO:0016042ISS-lipid catabolic process-
GO:0036149TAS-phosphatidylinositol acyl-chain remodeling-
GO:0036150TAS-phosphatidylserine acyl-chain remodeling-
GO:0036151TAS-phosphatidylcholine acyl-chain remodeling-
GO:0036152TAS-phosphatidylethanolamine acyl-chain remodeling-
GO:0045786IEA-negative regulation of cell cycle-
GO:0046485ISS-ether lipid metabolic process-
GO:1904177ISS-regulation of adipose tissue development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBQLN1PLA2G1611631716189514 Two-hybrid
UBQLN1PLA2G1611900716189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2179715
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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