AutismKB 2.0

Annotation Details for CORO1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CORO1A ( CLABP,CLIPINA,FLJ41407,HCORO1,MGC117380,TACO,p57 )
Gene Full Name: coronin, actin binding protein, 1A
Band: 16p11.2
Quick LinksEntrez ID:11151; OMIM: 605000; Uniprot ID:COR1A_HUMAN; ENSEMBL ID: ENSG00000102879; HGNC ID: 2252
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001772IDA-immunological synapse24760828
GO:0001891IDA-phagocytic cup17442961
GO:0005634IDANOTnucleus17341475
GO:0005737IDA-cytoplasm17341475
GO:0005769IEA-early endosome-
GO:0005829IEA-cytosol-
GO:0005884IDA-actin filament15800061
GO:0005886IDA-plasma membrane17341475
GO:0005911IEA-cell-cell junction-
GO:0016020IDA-membrane19946888
GO:0030027IDA-lamellipodium17442961
GO:0030424IEA-axon-
GO:0030670IEA-phagocytic vesicle membrane-
GO:0030864IDA-cortical actin cytoskeleton15800061
GO:0030864IDAcolocalizes_withcortical actin cytoskeleton24760828
GO:0043234IDA-protein complex11094157
GO:0045335IDA-phagocytic vesicle17442961
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003779IPI-actin binding23100250
GO:0003785IMP-actin monomer binding23100250
GO:0005515IPI-protein binding11094157
GO:0008022IPI-protein C-terminus binding9365277
GO:0008092ISS-cytoskeletal protein binding-
GO:0032036IPI-myosin heavy chain binding23100250
GO:0042803IDA-protein homodimerization activity15601263
GO:0043548IDA-phosphatidylinositol 3-kinase binding11094157
GO:0051015IDA-actin filament binding7758584
GO:0051015IMP-actin filament binding22364218
GO ID Evidence Qualifier GO_term References
GO:0001771IMPNOTimmunological synapse formation24760828
GO:0001845IMP-phagolysosome assembly12132654
GO:0006816IEA-calcium ion transport-
GO:0006909IMP-phagocytosis17442961
GO:0006928NAS-movement of cell or subcellular component17341475
GO:0007015IEA-actin filament organization-
GO:0008360IEA-regulation of cell shape-
GO:0030036IMP-actin cytoskeleton organization17442961
GO:0030335IEA-positive regulation of cell migration-
GO:0030595IEA-leukocyte chemotaxis-
GO:0031339IEA-negative regulation of vesicle fusion-
GO:0031589IMP-cell-substrate adhesion17442961
GO:0032796IEA-uropod organization-
GO:0032956IMP-regulation of actin cytoskeleton organization24760828
GO:0038180IEA-nerve growth factor signaling pathway-
GO:0042102IEA-positive regulation of T cell proliferation-
GO:0043029IEA-T cell homeostasis-
GO:0043320IMP-natural killer cell degranulation24760828
GO:0043524IEA-negative regulation of neuron apoptotic process-
GO:0045087NAS-innate immune response17341475
GO:0048873IEA-homeostasis of number of cells within a tissue-
GO:0050918IDA-positive chemotaxis17442961
GO:0051126IDA-negative regulation of actin nucleation17442961
GO:0051279IEA-regulation of release of sequestered calcium ion into cytosol-
GO:0061502IEA-early endosome to recycling endosome transport-
GO:0071353IEA-cellular response to interleukin-4-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CORO1AUBE2G211632217353931 Affinity Capture-MS
CORO1AUBE2G211317517353931 Affinity Capture-MS
DKK1CORO1A11632217353931 Affinity Capture-MS
DKK1CORO1A11659917353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1345961
  • Data Attributes: MGI curated and HomoloGene calculated
No data