AutismKB 2.0

Annotation Details for ADAMTS7


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Basic Information Top
Gene Symbol:ADAMTS7 ( ADAM-TS 7,ADAM-TS7,ADAMTS-7,DKFZp434H204 )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 7
Band: 15q25.1
Quick LinksEntrez ID:11173; OMIM: 605009; Uniprot ID:ATS7_HUMAN; ENSEMBL ID: ENSG00000136378; HGNC ID: 223
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005615IEA-extracellular space-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0009986IEA-cell surface-
GO ID Evidence Qualifier GO_term References
GO:0004222IDA-metalloendopeptidase activity18485748
GO:0005515IPI-protein binding18485748
GO:0008237TAS-metallopeptidase activity10464288
GO:0008270IEA-zinc ion binding-
GO ID Evidence Qualifier GO_term References
GO:0032331IDA-negative regulation of chondrocyte differentiation22247065
GO:0036066TAS-protein O-linked fucosylation-
GO:0051603IMP-proteolysis involved in cellular protein catabolic process18485748
GO:0071347IMP-cellular response to interleukin-118485748
GO:0071356IMP-cellular response to tumor necrosis factor18485748
GO:0071773IDA-cellular response to BMP stimulus22247065
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1347346
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018