AutismKB 2.0

Annotation Details for MAP4K5


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Basic Information Top
Gene Symbol:MAP4K5 ( GCKR,KHS,KHS1,MAPKKKK5 )
Gene Full Name: mitogen-activated protein kinase kinase kinase kinase 5
Band: 14q22.1
Quick LinksEntrez ID:11183; OMIM: 604923; Uniprot ID:M4K5_HUMAN; ENSEMBL ID: ENSG00000012983; HGNC ID: 6867
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm9038372
GO ID Evidence Qualifier GO_term References
GO:0004672TAS-protein kinase activity9038372
GO:0004674IDA-protein serine/threonine kinase activity9038372
GO:0004702IBA-signal transducer, downstream of receptor, with serine/threonine kinase activity-
GO:0005515IPI-protein binding9788432
GO:0005524IDA-ATP binding9038372
GO:0008349IEA-MAP kinase kinase kinase kinase activity-
GO ID Evidence Qualifier GO_term References
GO:0000185IEA-activation of MAPKKK activity-
GO:0006468IDA-protein phosphorylation9038372
GO:0007257TAS-activation of JUN kinase activity9038372
GO:0035556IDA-intracellular signal transduction9038372
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAP4K5CRK11635310648385 Affinity Capture-Western
MAP4K5CRK10778810648385 Affinity Capture-Western
MAP4K5CRKL10778910648385 Affinity Capture-Western; Reconstituted Complex
MAP4K5CRKL11635310648385 Affinity Capture-Western; Reconstituted Complex
MAP4K5GRB210914220936779 Two-hybrid
MAP4K5GRB211635320936779 Two-hybrid
MAP4K5HCK11635320936779 Two-hybrid
MAP4K5HCK10930520936779 Two-hybrid
MAP4K5TRAF211303810477597 Affinity Capture-Western
MAP4K5TRAF211635310477597 Affinity Capture-Western
MAP4K5COPS511618320936779 Two-hybrid
MAP4K5COPS511635320936779 Two-hybrid
ZNF440MAP4K512595320936779 Two-hybrid
ZNF440MAP4K511635320936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1925503
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6497'