AutismKB 2.0

Annotation Details for AKAP13


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Basic Information Top
Gene Symbol:AKAP13 ( AKAP-Lbc,ARHGEF13,BRX,FLJ11952,FLJ43341,HA-3,Ht31,LBC,PROTO-LB,PROTO-LBC,c-lbc )
Gene Full Name: A kinase (PRKA) anchor protein 13
Band: 15q25.3
Quick LinksEntrez ID:11214; OMIM: 604686; Uniprot ID:AKP13_HUMAN; ENSEMBL ID: ENSG00000170776; HGNC ID: 371
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005829IDA-cytosol11546812
GO:0005829TAS-cytosol-
GO:0005884IEA-actin filament-
GO:0005938IDA-cell cortex11546812
GO:0016020IDA-membrane19946888
GO:0030864IDAcolocalizes_withcortical actin cytoskeleton11546812
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004691IEA-cAMP-dependent protein kinase activity-
GO:0004871TAS-signal transducer activity8290273
GO:0005078IDA-MAP-kinase scaffold activity21224381
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089IDA-Rho guanyl-nucleotide exchange factor activity11546812
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding9627117
GO:0017048IPI-Rho GTPase binding25186459
GO:0032947IDA-protein complex scaffold23090968
GO:0046872IEA-metal ion binding-
GO:0051018IDA-protein kinase A binding11546812
GO ID Evidence Qualifier GO_term References
GO:0006468IEA-protein phosphorylation-
GO:0007186IDA-G-protein coupled receptor signaling pathway11546812
GO:0007507ISS-heart development-
GO:0010611IEA-regulation of cardiac muscle hypertrophy-
GO:0035025IDA-positive regulation of Rho protein signal transduction11546812
GO:0035025IMP-positive regulation of Rho protein signal transduction21224381
GO:0035556IEA-intracellular signal transduction-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043123IMP-positive regulation of I-kappaB kinase/NF-kappaB signaling23090968
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0051168IEA-nuclear export-
GO:0055007ISS-cardiac muscle cell differentiation-
GO:0060297ISS-regulation of sarcomere organization-
GO:0060348ISS-bone development-
GO:0071875IMP-adrenergic receptor signaling pathway21224381
GO:0071883IEA-activation of MAPK activity by adrenergic receptor signaling pathway-
GO:0086023ISS-adrenergic receptor signaling pathway involved in heart process-
GO:1900169IEA-regulation of glucocorticoid mediated signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AKAP13RHOA11638311696353 Affinity Capture-Western
AKAP13RHOA10688011696353 Affinity Capture-Western
AKAP13BAK111638317353931 Affinity Capture-MS
AKAP13BAK110705417353931 Affinity Capture-MS
AKAP13ESR11084039627117 Reconstituted Complex; Two-hybrid
AKAP13ESR11163839627117 Reconstituted Complex; Two-hybrid
AKAP13GNA1211638314636890 Affinity Capture-Western
AKAP13GNA1210903014636890 Affinity Capture-Western
AKAP13GNAQ11638311278452 Affinity Capture-Western
AKAP13GNAQ10903811278452 Affinity Capture-Western
AKAP13PPARA1163839627117 Reconstituted Complex
AKAP13PPARA1114619627117 Reconstituted Complex
AKAP13PRKAR2A1163831618839 12672969 Protein-peptide; Reconstituted Complex
AKAP13PRKAR2A1115621618839 12672969 Protein-peptide; Reconstituted Complex
AKAP13RANBP211183920936779 Two-hybrid
AKAP13RANBP211638320936779 Two-hybrid
AKAP13RXRB1163839627117 Reconstituted Complex
AKAP13RXRB1121699627117 Reconstituted Complex
AKAP13THRA1163839627117 Reconstituted Complex
AKAP13THRA1129239627117 Reconstituted Complex
AKAP13YWHAB11336117353931 Affinity Capture-MS
AKAP13YWHAB11638317353931 Affinity Capture-MS
AKAP13CTNNAL111638312270917 Affinity Capture-Western; Two-hybrid
AKAP13CTNNAL111426612270917 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2676556
  • Data Attributes: MGI curated and HomoloGene calculated
No data