Annotation Details for DUSP10
Basic Information Top
| Gene Symbol: | DUSP10 ( MKP-5,MKP5 ) |
|---|---|
| Gene Full Name: | dual specificity phosphatase 10 |
| Band: | 1q41 |
| Quick Links | Entrez ID:11221; OMIM: 608867; Uniprot ID:DUS10_HUMAN; ENSEMBL ID: ENSG00000143507; HGNC ID: 3065 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005634 | TAS | - | nucleus | 10391943 |
| GO:0005654 | IDA | - | nucleoplasm | - |
| GO:0005737 | TAS | - | cytoplasm | 10391943 |
| GO:0005794 | IDA | - | Golgi apparatus | - |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0016607 | IDA | - | nuclear speck | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0004721 | TAS | - | phosphoprotein phosphatase activity | 10391943 |
| GO:0004725 | IEA | - | protein tyrosine phosphatase activity | - |
| GO:0016791 | IDA | - | phosphatase activity | 16806267 |
| GO:0017017 | IEA | - | MAP kinase tyrosine/serine/threonine phosphatase activity | - |
| GO:0033549 | IDA | - | MAP kinase phosphatase activity | 22375048 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0000188 | IDA | - | inactivation of MAPK activity | 22375048 |
| GO:0002819 | IEA | - | regulation of adaptive immune response | - |
| GO:0006470 | IDA | - | protein dephosphorylation | 22375048 |
| GO:0006950 | TAS | - | response to stress | 10391943 |
| GO:0007254 | TAS | - | JNK cascade | 10391943 |
| GO:0016311 | IDA | - | dephosphorylation | 24531476 |
| GO:0032496 | IEA | - | response to lipopolysaccharide | - |
| GO:0035335 | IEA | - | peptidyl-tyrosine dephosphorylation | - |
| GO:0043508 | IBA | - | negative regulation of JUN kinase activity | - |
| GO:0044387 | IEA | - | negative regulation of protein kinase activity by regulation of protein phosphorylation | - |
| GO:0045591 | IMP | - | positive regulation of regulatory T cell differentiation | 22387553 |
| GO:0048709 | IEA | - | oligodendrocyte differentiation | - |
| GO:0048715 | IEA | - | negative regulation of oligodendrocyte differentiation | - |
| GO:0060266 | IEA | - | negative regulation of respiratory burst involved in inflammatory response | - |
| GO:0090335 | IEA | - | regulation of brown fat cell differentiation | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| DUSP10 | MAPK14 | 107819 | 10391943 11157753 11359773 20936779 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
| DUSP10 | MAPK14 | 116389 | 10391943 11157753 11359773 20936779 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
| DUSP10 | MAPK8 | 111585 | 10391943 | Biochemical Activity; Two-hybrid |
| DUSP10 | MAPK8 | 116389 | 10391943 | Biochemical Activity; Two-hybrid |
| DUSP10 | MAPK9 | 116389 | 11359773 | Affinity Capture-Western |
| DUSP10 | MAPK9 | 111587 | 11359773 | Affinity Capture-Western |
| DUSP10 | MAPK10 | 116389 | 11359773 | Affinity Capture-Western |
| DUSP10 | MAPK10 | 111588 | 11359773 | Affinity Capture-Western |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| DUSP10 | MAPK14 | 257582 | 10391943 | An unspecified isoform of MAPK14 interacts with DUSP10. |
| DUSP10 | MAPK8 | 257581 | 10391943 | An unspecified isoform of MAPK8 interacts with DUSP10. This interaction was modelled on a demonstrated interaction between MAPK8 from an unspecified species and human DUSP10. |
| No data |
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