AutismKB 2.0

Annotation Details for ZHX1


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Basic Information Top
Gene Symbol:ZHX1 ( - )
Gene Full Name: zinc fingers and homeoboxes 1
Band: 8q24.13
Quick LinksEntrez ID:11244; OMIM: 604764; Uniprot ID:ZHX1_HUMAN; ENSEMBL ID: ENSG00000165156; HGNC ID: 12871
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus12237128
GO:0005654IDA-nucleoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding12237128
GO:0003714IDA-transcription corepressor activity17303076
GO:0005515IPI-protein binding10571058
GO:0046872IEA-metal ion binding-
GO:0046982IDA-protein heterodimerization activity12659632
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter17303076
GO:0006351IEA-transcription, DNA-templated-
GO:0030154IEA-cell differentiation-
GO:0045892IDA-negative regulation of transcription, DNA-templated12237128
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZHX1CREB111640620936779 Two-hybrid
ZHX1CREB110777520936779 Two-hybrid
ZHX1CSNK2A110784116169070 Two-hybrid
ZHX1CSNK2A111640616169070 Two-hybrid
ZHX1DLST10808716169070 Two-hybrid
ZHX1DLST11640616169070 Two-hybrid
ZHX1EFNA211640612659632 Two-hybrid
ZHX1EFNA210826312659632 Two-hybrid
ZHX1GNG1111640616169070 Two-hybrid
ZHX1GNG1110905316169070 Two-hybrid
ZHX1HSPE111640616169070 Two-hybrid
ZHX1HSPE110956816169070 Two-hybrid
ZHX1IDH111640616169070 Two-hybrid
ZHX1IDH110964316169070 Two-hybrid
ZHX1LAMA411640616169070 Two-hybrid
ZHX1LAMA411010416169070 Two-hybrid
ZHX1NACA11640616169070 Two-hybrid
ZHX1NACA11074816169070 Two-hybrid
ZHX1NFYA11086610441475 10571058 Reconstituted Complex; Two-hybrid
ZHX1NFYA11640610441475 10571058 Reconstituted Complex; Two-hybrid
ZHX1PNP11092116169070 Two-hybrid
ZHX1PNP11640616169070 Two-hybrid
ZHX1PAFAH1B311640616169070 Two-hybrid
ZHX1PAFAH1B311108716169070 Two-hybrid
ZHX1PEX1411640616169070 Two-hybrid
ZHX1PEX1411121816169070 Two-hybrid
ZHX1SERPINB911640616169070 Two-hybrid
ZHX1SERPINB911129016169070 Two-hybrid
ZHX1PIGC11640616169070 Two-hybrid
ZHX1PIGC11129716169070 Two-hybrid
ZHX1PSMD1111640616169070 Two-hybrid
ZHX1PSMD1111168916169070 Two-hybrid
ZHX1SAT111640616169070 Two-hybrid
ZHX1SAT111221016169070 Two-hybrid
ZHX1ATXN111221712659632 Two-hybrid
ZHX1ATXN111640612659632 Two-hybrid
ZHX1TERF111640616169070 Two-hybrid
ZHX1TERF111287216169070 Two-hybrid
ZHX1ZYX11640612659632 Two-hybrid
ZHX1ZYX11356912659632 Two-hybrid
ZHX1ELL11382812659632 Two-hybrid
ZHX1ELL11640612659632 Two-hybrid
ZHX1BHLHE4011640616169070 Two-hybrid
ZHX1BHLHE4011412316169070 Two-hybrid
ZHX1AKR1C311640616169070 Two-hybrid
ZHX1AKR1C311419616169070 Two-hybrid
ZHX1DYNLL111420616169070 Two-hybrid
ZHX1DYNLL111640616169070 Two-hybrid
ZHX1TNFRSF10C11640616169070 Two-hybrid
ZHX1TNFRSF10C11432216169070 Two-hybrid
ZHX1MPHOSPH611640616169070 Two-hybrid
ZHX1MPHOSPH611549516169070 Two-hybrid
ZHX1ZMYND1111640612659632 Two-hybrid
ZHX1ZMYND1111598912659632 Two-hybrid
ZHX1ZHX111640612062805 12237128 12659632 Reconstituted Complex; Two-hybrid
ZHX3ZHX111668812659632 Reconstituted Complex; Two-hybrid
ZHX3ZHX111640612659632 Reconstituted Complex; Two-hybrid
TARDBPZHX111640616169070 Two-hybrid
TARDBPZHX111700316169070 Two-hybrid
TOLLIPZHX111640616169070 Two-hybrid
TOLLIPZHX111997816169070 Two-hybrid
WDR33ZHX112062016169070 Two-hybrid
WDR33ZHX111640616169070 Two-hybrid
LYARZHX112078016169070 Two-hybrid
LYARZHX111640616169070 Two-hybrid
UTP3ZHX112134216169070 Two-hybrid
UTP3ZHX111640616169070 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
ZHX1NFYA19681010571058 NF-YA interacts with ZHX1. This interaction was modeled on a demonstrated interaction between NF-YA from an unspecified species and ZHX1 from human.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109271
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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