AutismKB 2.0

Annotation Details for PACSIN2


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Basic Information Top
Gene Symbol:PACSIN2 ( SDPII )
Gene Full Name: protein kinase C and casein kinase substrate in neurons 2
Band: 22q13.2
Quick LinksEntrez ID:11252; OMIM: 604960; Uniprot ID:PACN2_HUMAN; ENSEMBL ID: ENSG00000100266; HGNC ID: 8571
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm10431838
GO:0005769IEA-early endosome-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0005886IDA-plasma membrane-
GO:0005901IDA-caveola21610094
GO:0005911IEA-cell-cell junction-
GO:0005925IDA-focal adhesion21423176
GO:0016607IDA-nuclear speck-
GO:0019898ISS-extrinsic component of membrane-
GO:0030659IEA-cytoplasmic vesicle membrane-
GO:0032587IEA-ruffle membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0055038IDA-recycling endosome membrane23596323
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005215TAS-transporter activity10431838
GO:0005515IPI-protein binding16189514
GO:0008092IEA-cytoskeletal protein binding-
GO:0042802IPI-identical protein binding16189514
GO:0045296IDA-cadherin binding25468996
GO:0070300IDA-phosphatidic acid binding23596323
GO ID Evidence Qualifier GO_term References
GO:0030036IEA-actin cytoskeleton organization-
GO:0030100IBA-regulation of endocytosis-
GO:0036010IMP-protein localization to endosome23596323
GO:0045806IEA-negative regulation of endocytosis-
GO:0048858ISS-cell projection morphogenesis-
GO:0061024TAS-membrane organization-
GO:0070836IMP-caveola assembly21610094
GO:0072584IMP-caveolin-mediated endocytosis21610094
GO:0097320IDA-plasma membrane tubulation23596323
GO:0097320ISS-plasma membrane tubulation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PACSIN2FASLG11641312023017 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PACSIN2FASLG10685212023017 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PACSIN2CARS10728319041431 Affinity Capture-MS
PACSIN2CARS11641319041431 Affinity Capture-MS
PACSIN2DNM110809911082044 Reconstituted Complex
PACSIN2DNM111641311082044 Reconstituted Complex
PACSIN2DNM211641319041431 Affinity Capture-MS
PACSIN2DNM210812219041431 Affinity Capture-MS
PACSIN2HSPA1A11641319041431 Affinity Capture-MS
PACSIN2HSPA1A10953519041431 Affinity Capture-MS
PACSIN2HSPA811641319041431 Affinity Capture-MS
PACSIN2HSPA810954419041431 Affinity Capture-MS
PACSIN2WAS11329319041431 Affinity Capture-MS
PACSIN2WAS11641319041431 Affinity Capture-MS
PACSIN2WIPF111329519041431 Affinity Capture-MS
PACSIN2WIPF111641319041431 Affinity Capture-MS
PACSIN2SYNJ111641311082044 Reconstituted Complex
PACSIN2SYNJ111438811082044 Reconstituted Complex
PACSIN2WASL11446611082044 Reconstituted Complex
PACSIN2WASL11641311082044 Reconstituted Complex
PACSIN2KHDRBS111641319041431 Affinity Capture-MS
PACSIN2KHDRBS111590019041431 Affinity Capture-MS
PACSIN2PACSIN211641311082044 16189514 Reconstituted Complex; Two-hybrid
PACSIN3PACSIN211889611082044 Reconstituted Complex; Two-hybrid
PACSIN3PACSIN211641311082044 Reconstituted Complex; Two-hybrid
PACSIN1PACSIN211641311082044 16189514 20936779 Reconstituted Complex; Two-hybrid
PACSIN1PACSIN211901811082044 16189514 20936779 Reconstituted Complex; Two-hybrid
CYFIP2PACSIN211794519041431 Affinity Capture-MS
CYFIP2PACSIN211641319041431 Affinity Capture-MS
SBK1PACSIN213260919041431 Affinity Capture-MS
SBK1PACSIN211641319041431 Affinity Capture-MS
ASAP1PACSIN211912619041431 Affinity Capture-MS
ASAP1PACSIN211641319041431 Affinity Capture-MS
APBB1IPPACSIN211641319041431 Affinity Capture-MS
APBB1IPPACSIN212001219041431 Affinity Capture-MS
MICALL1PACSIN212450419041431 Affinity Capture-MS
MICALL1PACSIN211641319041431 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1345153
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2596'