AutismKB 2.0

Annotation Details for STX1B


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Basic Information Top
Gene Symbol:STX1B ( STX1B1,STX1B2 )
Gene Full Name: syntaxin 1B
Band: 16p11.2
Quick LinksEntrez ID:112755; OMIM: 601485; Uniprot ID:STX1B_HUMAN; ENSEMBL ID: ENSG00000099365; HGNC ID: 18539
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005815IEA-microtubule organizing center-
GO:0005819IEA-spindle-
GO:0005829TAS-cytosol-
GO:0005886IBA-plasma membrane-
GO:0005886ISS-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0008021IBA-synaptic vesicle-
GO:0016020ISS-membrane-
GO:0016021IBA-integral component of membrane-
GO:0031201IBA-SNARE complex-
GO:0048787IEA-presynaptic active zone membrane-
GO ID Evidence Qualifier GO_term References
GO:0000149IBA-SNARE binding-
GO:0005102IEA-receptor binding-
GO:0005484IBA-SNAP receptor activity-
GO:0019901ISS-protein kinase binding-
GO:0019904IEA-protein domain specific binding-
GO ID Evidence Qualifier GO_term References
GO:0001956ISS-positive regulation of neurotransmitter secretion-
GO:0006886IBA-intracellular protein transport-
GO:0006904ISS-vesicle docking involved in exocytosis-
GO:0010468ISS-regulation of gene expression-
GO:0010807ISS-regulation of synaptic vesicle priming-
GO:0010977ISS-negative regulation of neuron projection development-
GO:0016081ISS-synaptic vesicle docking-
GO:0031629IBA-synaptic vesicle fusion to presynaptic active zone membrane-
GO:0048278IBA-vesicle docking-
GO:0048791IEA-calcium ion-regulated exocytosis of neurotransmitter-
GO:0060025ISS-regulation of synaptic activity-
GO:0061669IEA-spontaneous neurotransmitter secretion-
GO:0098967IEA-exocytic insertion of neurotransmitter receptor to postsynaptic membrane-
GO:1903422IEA-negative regulation of synaptic vesicle recycling-
GO:1904050IEA-positive regulation of spontaneous neurotransmitter secretion-
GO:1905302ISS-negative regulation of macropinocytosis-
GO:2000463ISS-positive regulation of excitatory postsynaptic potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STX1BSTXBP111268112093152 Reconstituted Complex
STX1BSTXBP112520312093152 Reconstituted Complex
STX1BVAMP112520312093152 Two-hybrid
STX1BVAMP111271012093152 Two-hybrid
STX1BVAMP212520312093152 Two-hybrid
STX1BVAMP211271112093152 Two-hybrid
STX1BSNAP2312520312651853 Reconstituted Complex
STX1BSNAP2311430312651853 Reconstituted Complex
STX1BVAPB11465012651853 Reconstituted Complex
STX1BVAPB12520312651853 Reconstituted Complex
STX1BUNC13B1157598999968 Co-fractionation; Two-hybrid
STX1BUNC13B1252038999968 Co-fractionation; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1930705
  • Data Attributes: MGI curated and HomoloGene calculated
No data