AutismKB 2.0

Annotation Details for CHRM1


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Basic Information Top
Gene Symbol:CHRM1 ( HM1,M1,M1R,MGC30125 )
Gene Full Name: cholinergic receptor, muscarinic 1
Band: 11q12.3
Quick LinksEntrez ID:1128; OMIM: 118510; Uniprot ID:ACM1_HUMAN; ENSEMBL ID: ENSG00000168539; HGNC ID: 1950
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IEA-integral component of plasma membrane-
GO:0014069IEA-postsynaptic density-
GO:0016020TAS-membrane7925360
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0043679IEA-axon terminus-
GO:0045202IBA-synapse-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004435TAS-phosphatidylinositol phospholipase C activity9614217
GO:0008144IEA-drug binding-
GO:0016907IBA-G-protein coupled acetylcholine receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0003056IBA-regulation of vascular smooth muscle contraction-
GO:0006464TAS-cellular protein modification process1411529
GO:0007165TAS-signal transduction3443095
GO:0007186TAS-G-protein coupled receptor signaling pathway7925360
GO:0007197IBA-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-
GO:0007205TAS-protein kinase C-activating G-protein coupled receptor signaling pathway9603968
GO:0007207TAS-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway8139539
GO:0007213TAS-G-protein coupled acetylcholine receptor signaling pathway8139539
GO:0007271IBA-synaptic transmission, cholinergic-
GO:0007274IEA-neuromuscular synaptic transmission-
GO:0007399TAS-nervous system development2739737
GO:0008283TAS-cell proliferation1905013
GO:0008284TAS-positive regulation of cell proliferation2739737
GO:0040012IEA-regulation of locomotion-
GO:0043270IGI-positive regulation of ion transport14657398
GO:0046541IEA-saliva secretion-
GO:0050890IEA-cognition-
GO:0090316IEA-positive regulation of intracellular protein transport-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CHRM1rs2067477 Gene overview in AlzGene
No data
Gene Symbol Poly Names Gene overview in SZGene
CHRM1rs2067477 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88396
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070705-188'