AutismKB 2.0

Annotation Details for CHRM2


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Basic Information Top
Gene Symbol:CHRM2 ( FLJ43243,HM2,MGC120006,MGC120007 )
Gene Full Name: cholinergic receptor, muscarinic 2
Band: 7q33
Quick LinksEntrez ID:1129; OMIM: 118493; Uniprot ID:ACM2_HUMAN; ENSEMBL ID: ENSG00000181072; HGNC ID: 1951
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane24256733
GO:0016021IDA-integral component of membrane11566136
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0030665TAS-clathrin-coated vesicle membrane-
GO:0032279IEA-asymmetric synapse-
GO:0032280IEA-symmetric synapse-
GO:0043025IEA-neuronal cell body-
GO:0043679IEA-axon terminus-
GO:0045202IBA-synapse-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0008144IEA-drug binding-
GO:0016907IDA-G-protein coupled acetylcholine receptor activity24256733
GO:1990763IPI-arrestin family protein binding11566136
GO ID Evidence Qualifier GO_term References
GO:0006940IBA-regulation of smooth muscle contraction-
GO:0007186TAS-G-protein coupled receptor signaling pathway9603968
GO:0007187TAS-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger10895079
GO:0007188TAS-adenylate cyclase-modulating G-protein coupled receptor signaling pathway8139539
GO:0007197IBA-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-
GO:0007207TAS-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway2739737
GO:0007213IDA-G-protein coupled acetylcholine receptor signaling pathway24256733
GO:0007271IBA-synaptic transmission, cholinergic-
GO:0007399TAS-nervous system development2739737
GO:0008016IBA-regulation of heart contraction-
GO:0009615IEP-response to virus16548883
GO:0061024TAS-membrane organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SETCHRM210755117065150 Reconstituted Complex
SETCHRM211231617065150 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88397
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030314-1'