AutismKB 2.0

Annotation Details for CHRM3


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Basic Information Top
Gene Symbol:CHRM3 ( HM3 )
Gene Full Name: cholinergic receptor, muscarinic 3
Band: 1q43
Quick LinksEntrez ID:1131; OMIM: 118494; Uniprot ID:ACM3_HUMAN; ENSEMBL ID: ENSG00000133019; HGNC ID: 1952
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane-
GO:0016323IEA-basolateral plasma membrane-
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0032279IEA-asymmetric synapse-
GO:0043679IEA-axon terminus-
GO:0045202IBA-synapse-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004435TAS-phosphatidylinositol phospholipase C activity1905013
GO:0004872TAS-receptor activity10940357
GO:0005515IPI-protein binding19575010
GO:0008144IEA-drug binding-
GO:0016907IBA-G-protein coupled acetylcholine receptor activity-
GO:0016907ISS-G-protein coupled acetylcholine receptor activity-
GO:0042166ISS-acetylcholine binding-
GO ID Evidence Qualifier GO_term References
GO:0003056IBA-regulation of vascular smooth muscle contraction-
GO:0006464TAS-cellular protein modification process10051746
GO:0006939IEA-smooth muscle contraction-
GO:0007165TAS-signal transduction10940357
GO:0007186TAS-G-protein coupled receptor signaling pathway9603968
GO:0007197IBA-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-
GO:0007207IBA-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway-
GO:0007213ISS-G-protein coupled acetylcholine receptor signaling pathway-
GO:0007271IBA-synaptic transmission, cholinergic-
GO:0007399TAS-nervous system development2739737
GO:0008283TAS-cell proliferation8063729
GO:0045987IEA-positive regulation of smooth muscle contraction-
GO:0046541IEA-saliva secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CHRM3ARF110755312799371 Affinity Capture-Western; Reconstituted Complex
CHRM3ARF110687012799371 Affinity Capture-Western; Reconstituted Complex
CHRM3ARF610755312799371 Affinity Capture-Western; Reconstituted Complex
CHRM3ARF610687712799371 Affinity Capture-Western; Reconstituted Complex
CSNK1A1CHRM310755310777483 Reconstituted Complex
CSNK1A1CHRM310783610777483 Reconstituted Complex
SETCHRM310755317065150 Affinity Capture-Western; Reconstituted Complex
SETCHRM311231617065150 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88398
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090410-4'