AutismKB 2.0

Annotation Details for U2AF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:U2AF2 ( U2AF65 )
Gene Full Name: U2 small nuclear RNA auxiliary factor 2
Band: 19q13.43
Quick LinksEntrez ID:11338; OMIM: 191318; Uniprot ID:U2AF2_HUMAN; ENSEMBL ID: ENSG00000063244; HGNC ID: 23156
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000243IBA-commitment complex-
GO:0000974IDAcolocalizes_withPrp19 complex21536736
GO:0005634IDA-nucleus1824937
GO:0005654TAS-nucleoplasm-
GO:0005681IDA-spliceosomal complex9731529
GO:0016607IDA-nuclear speck1824937
GO:0071004IDA-U2-type prespliceosome2531895
GO:0089701IDA-U2AF1824937
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding9237760
GO:0008187IBA-poly-pyrimidine tract binding-
GO:0019899IPI-enzyme binding19574390
GO:0030628IDA-pre-mRNA 3'-splice site binding2531895
GO:0070742IEA-C2H2 zinc finger domain binding-
GO ID Evidence Qualifier GO_term References
GO:0000398IC-mRNA splicing, via spliceosome9731529
GO:0000398IDA-mRNA splicing, via spliceosome1824937
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006369TAS-termination of RNA polymerase II transcription-
GO:0006397TAS-mRNA processing1538748
GO:0006405TAS-RNA export from nucleus-
GO:0006406TAS-mRNA export from nucleus-
GO:0031124TAS-mRNA 3'-end processing-
GO:0031397IDA-negative regulation of protein ubiquitination24389012
GO:0031397IMP-negative regulation of protein ubiquitination24389012
GO:0033120IDA-positive regulation of RNA splicing21536736
GO:0048025IDA-negative regulation of mRNA splicing, via spliceosome15009664
GO:1903146IMP-regulation of mitophagy24912190
GO:1903955IMP-positive regulation of protein targeting to mitochondrion24912190
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
U2AF2APBB111646616055720 Affinity Capture-MS
U2AF2APBB110681916055720 Affinity Capture-MS
U2AF2DVL211646616189514 Two-hybrid
U2AF2DVL210818916189514 Two-hybrid
U2AF2PIN111646616055720 Affinity Capture-MS
U2AF2PIN111131716055720 Affinity Capture-MS
U2AF2SRSF111646616189514 Two-hybrid
U2AF2SRSF111232416189514 Two-hybrid
U2AF2SRPK21126119472028 16189514 Biochemical Activity; Two-hybrid
U2AF2SRPK21164669472028 16189514 Biochemical Activity; Two-hybrid
U2AF2U2AF11164661388271 16189514 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2U2AF11131571388271 16189514 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2WT11133279784496 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2WT11164669784496 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2SF11133689150140 9512519 16189514 Reconstituted Complex; Two-hybrid
U2AF2SF11164669150140 9512519 16189514 Reconstituted Complex; Two-hybrid
U2AF2SF3A211382612234937 Affinity Capture-MS
U2AF2SF3A211646612234937 Affinity Capture-MS
U2AF2SRSF2IP1146109447963 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2SRSF2IP1164669447963 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
U2AF2SRSF111147098816452 Reconstituted Complex; Two-hybrid
U2AF2SRSF111164668816452 Reconstituted Complex; Two-hybrid
U2AF2TCERG111612015456888 16055720 Affinity Capture-MS
U2AF2TCERG111646615456888 16055720 Affinity Capture-MS
U2AF2RNPS111612517353931 Affinity Capture-MS
U2AF2RNPS111646617353931 Affinity Capture-MS
PRPF40AU2AF212079216055720 Affinity Capture-MS
PRPF40AU2AF211646616055720 Affinity Capture-MS
PUF60U2AF211646616189514 17353931 Affinity Capture-MS; Two-hybrid
PUF60U2AF211650216189514 17353931 Affinity Capture-MS; Two-hybrid
DPPA2U2AF212740716189514 Two-hybrid
DPPA2U2AF211646616189514 Two-hybrid
BEND7U2AF211646616189514 Two-hybrid
BEND7U2AF212879716189514 Two-hybrid
KIAA0907U2AF211646616189514 Two-hybrid
KIAA0907U2AF211655516189514 Two-hybrid
CHIC2U2AF211646616189514 Two-hybrid
CHIC2U2AF211771616189514 Two-hybrid
C1orf190U2AF211646616189514 Two-hybrid
C1orf190U2AF213907116189514 Two-hybrid
THAP1U2AF211646616189514 Two-hybrid
THAP1U2AF212044816189514 Two-hybrid
GIGYF2U2AF211752020696395 Affinity Capture-MS
GIGYF2U2AF211646620696395 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
U2AF2SF11515909512519 U2AF65 interacts with an unspecified isoform of SF1 (mBBP).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98886
  • Data Attributes: MGI curated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1881'