AutismKB 2.0

Annotation Details for CISH


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Basic Information Top
Gene Symbol:CISH ( CIS,CIS-1,G18,SOCS )
Gene Full Name: cytokine inducible SH2-containing protein
Band: 3p21.2
Quick LinksEntrez ID:1154; OMIM: 602441; Uniprot ID:CISH_HUMAN; ENSEMBL ID: ENSG00000114737; HGNC ID: 1984
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO:0004860IBA-protein kinase inhibitor activity-
GO:0005515IPI-protein binding16273093
GO ID Evidence Qualifier GO_term References
GO:0001558NAS-regulation of cell growth9465889
GO:0006469IBA-negative regulation of protein kinase activity-
GO:0007205IEA-protein kinase C-activating G-protein coupled receptor signaling pathway-
GO:0016567IEA-protein ubiquitination-
GO:0019221IBA-cytokine-mediated signaling pathway-
GO:0035556NAS-intracellular signal transduction10902923
GO:0043687TAS-post-translational protein modification-
GO:0046426IBA-negative regulation of JAK-STAT cascade-
GO:0046627IBA-negative regulation of insulin receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL3RACISH1075747796808 Affinity Capture-Western
IL3RACISH1097787796808 Affinity Capture-Western
EPORCISH1083717796808 15644415 16961462 Affinity Capture-Western; PCA; Reconstituted Complex
EPORCISH1075747796808 15644415 16961462 Affinity Capture-Western; PCA; Reconstituted Complex
IL2RBCISH10757410514520 Affinity Capture-Western
IL2RBCISH10977510514520 Affinity Capture-Western
GHRCISH10895710585430 Affinity Capture-Western; Reconstituted Complex
GHRCISH10757410585430 Affinity Capture-Western; Reconstituted Complex
TCEB1CISH11278316961462 Affinity Capture-MS
TCEB1CISH10757416961462 Affinity Capture-MS
TCEB2CISH10757416961462 Affinity Capture-MS
TCEB2CISH11278516961462 Affinity Capture-MS
CUL5CISH11374316961462 Affinity Capture-MS
CUL5CISH10757416961462 Affinity Capture-MS
MYD88CISH11070016961462 Affinity Capture-Western; PCA
MYD88CISH10757416961462 Affinity Capture-Western; PCA
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103159
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050907-1'