AutismKB 2.0

Annotation Details for RASGRP4


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Basic Information Top
Gene Symbol:RASGRP4 ( - )
Gene Full Name: RAS guanyl releasing protein 4
Band: 19q13.1
Quick LinksEntrez ID:115727; OMIM: 607320; Uniprot ID:GRP4_HUMAN; ENSEMBL ID: ENSG00000171777; HGNC ID: 18958
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane11880369
GO:0016020IDA-membrane11880369
GO ID Evidence Qualifier GO_term References
GO:0005088IDA-Ras guanyl-nucleotide exchange factor activity11880369
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005509IEA-calcium ion binding-
GO:0019992TAS-diacylglycerol binding11880369
GO:0030742NAS-GTP-dependent protein binding11880369
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0007169NAS-transmembrane receptor protein tyrosine kinase signaling pathway11880369
GO:0007202NAS-activation of phospholipase C activity11880369
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0008277NAS-regulation of G-protein coupled receptor protein signaling pathway11880369
GO:0008283IDA-cell proliferation11880369
GO:0009991IDA-response to extracellular stimulus11880369
GO:0016049IDA-cell growth11880369
GO:0030099TAS-myeloid cell differentiation11880369
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046579IDA-positive regulation of Ras protein signal transduction11880369
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2386851
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018