AutismKB 2.0

Annotation Details for ADCYAP1


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Basic Information Top
Gene Symbol:ADCYAP1 ( MGC126852,PACAP )
Gene Full Name: adenylate cyclase activating polypeptide 1 (pituitary)
Band: 18p11.32
Quick LinksEntrez ID:116; OMIM: 102980; Uniprot ID:PACA_HUMAN; ENSEMBL ID: ENSG00000141433; HGNC ID: 241
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005622IEA-intracellular-
GO:0043195IEA-terminal bouton-
GO ID Evidence Qualifier GO_term References
GO:0005057IEA-signal transducer activity, downstream of receptor-
GO:0005102IPI-receptor binding7680413
GO:0005184IDA-neuropeptide hormone activity23800469
GO:0005515IPI-protein binding25451228
GO:0016521IDA-pituitary adenylate cyclase activating polypeptide activity9603988
GO:0031858IEA-pituitary adenylate cyclase-activating polypeptide receptor binding-
GO:0051428IDA-peptide hormone receptor binding11175907
GO:0051428IPI-peptide hormone receptor binding17470806
GO ID Evidence Qualifier GO_term References
GO:0001541IEA-ovarian follicle development-
GO:0001662IEA-behavioral fear response-
GO:0001821IEA-histamine secretion-
GO:0002865IEA-negative regulation of acute inflammatory response to antigenic stimulus-
GO:0002878IEA-negative regulation of acute inflammatory response to non-antigenic stimulus-
GO:0007190TAS-activation of adenylate cyclase activity1730060
GO:0007204ISS-positive regulation of cytosolic calcium ion concentration-
GO:0007218IDA-neuropeptide signaling pathway23800469
GO:0007267TAS-cell-cell signaling2302217
GO:0007565TAS-female pregnancy10698193
GO:0008277IDA-regulation of G-protein coupled receptor protein signaling pathway11175907
GO:0008284IEA-positive regulation of cell proliferation-
GO:0010579IDA-positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway9603988
GO:0010656IEA-negative regulation of muscle cell apoptotic process-
GO:0010976IEA-positive regulation of neuron projection development-
GO:0019233IEA-sensory perception of pain-
GO:0019933IMP-cAMP-mediated signaling23800469
GO:0021983IEA-pituitary gland development-
GO:0030073ISS-insulin secretion-
GO:0031175IDA-neuron projection development23800469
GO:0032755IEA-positive regulation of interleukin-6 production-
GO:0032880IDA-regulation of protein localization9603988
GO:0034260IEA-negative regulation of GTPase activity-
GO:0042594IEA-response to starvation-
GO:0043267IEA-negative regulation of potassium ion transport-
GO:0043547IDA-positive regulation of GTPase activity23800469
GO:0045471IEA-response to ethanol-
GO:0045786IEA-negative regulation of cell cycle-
GO:0045860IDA-positive regulation of protein kinase activity23800469
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter23800469
GO:0046034IEA-ATP metabolic process-
GO:0051968IEA-positive regulation of synaptic transmission, glutamatergic-
GO:0060078IEA-regulation of postsynaptic membrane potential-
GO:0060124ISS-positive regulation of growth hormone secretion-
GO:0060253IEA-negative regulation of glial cell proliferation-
GO:0070374IDA-positive regulation of ERK1 and ERK2 cascade23800469
GO:0070445IEA-regulation of oligodendrocyte progenitor proliferation-
GO:0071385IEA-cellular response to glucocorticoid stimulus-
GO:0071651IDA-positive regulation of chemokine (C-C motif) ligand 5 production24696163
GO:0090274IEA-positive regulation of somatostatin secretion-
GO:0097755IEA-positive regulation of blood vessel diameter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CPAMD8ADCYAP11066291335692 Protein-peptide
CPAMD8ADCYAP11180331335692 Protein-peptide
SCTRADCYAP11122481335692 Protein-peptide
SCTRADCYAP11066291335692 Protein-peptide
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
ADCYAP1rs2846584 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
ADCYAP1rs1610037, rs1893153, rs1893154, rs2231181, rs2231185, rs2846584, rs2856966, rs928978 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:105094
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020809-4'