AutismKB 2.0

Annotation Details for GRIN3A


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Basic Information Top
Gene Symbol:GRIN3A ( FLJ45414,NMDAR-L,NR3A )
Gene Full Name: glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
Band: 9q31.1
Quick LinksEntrez ID:116443; OMIM: 606650; Uniprot ID:NMD3A_HUMAN; ENSEMBL ID: ENSG00000198785; HGNC ID: 16767
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0014069IEA-postsynaptic density-
GO:0016020IDA-membrane17997397
GO:0016021NAS-integral component of membrane11880201
GO:0017146IDA-NMDA selective glutamate receptor complex17997397
GO:0030054IEA-cell junction-
GO:0043005IDA-neuron projection17658481
GO:0043025IDA-neuronal cell body17658481
GO:0045202IDA-synapse17658481
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004972IDA-NMDA glutamate receptor activity17502428
GO:0004972ISScontributes_toNMDA glutamate receptor activity-
GO:0005234IEA-extracellular-glutamate-gated ion channel activity-
GO:0005262IEA-calcium channel activity-
GO:0005515IPI-protein binding17658481
GO:0016594IDA-glycine binding17320117
GO:0042802IPI-identical protein binding17997397
GO:0051721ISS-protein phosphatase 2A binding-
GO ID Evidence Qualifier GO_term References
GO:0006816ISS-calcium ion transport-
GO:0016358IEA-dendrite development-
GO:0034765IEA-regulation of ion transmembrane transport-
GO:0035235IEA-ionotropic glutamate receptor signaling pathway-
GO:0045471IDA-response to ethanol17502428
GO:0060079IEA-excitatory postsynaptic potential-
GO:0060134IEA-prepulse inhibition-
GO:0070588IEA-calcium ion transmembrane transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRIN3ACEBPA10747917082780 Affinity Capture-MS
GRIN3ACEBPA12550817082780 Affinity Capture-MS
GRIN3AGRIN110915912391275 Affinity Capture-Western
GRIN3AGRIN112550812391275 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
GRIN3Ars10989563, rs3739722 Gene overview in AlzGene
No data
Gene Symbol Poly Names Gene overview in SZGene
GRIN3AGRIN3A_-413A/G, GRIN3A_-415C/G, GRIN3A_N1073I, GRIN3A_R480G, rs10512285, rs10989563, rs10989564, rs10989589, rs10989591, rs13284303, rs1337676, rs1337677, rs16920497, rs1983812, rs2506354, rs33945236, rs3739722, rs62577464, rs7030238, rs942142 Gene overview in SZGene
Animal Model Top
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018