AutismKB 2.0

Annotation Details for LRG1


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Basic Information Top
Gene Symbol:LRG1 ( HMFT1766,LRG )
Gene Full Name: leucine-rich alpha-2-glycoprotein 1
Band: 19p13.3
Quick LinksEntrez ID:116844; OMIM: 611289; Uniprot ID:A2GL_HUMAN; ENSEMBL ID: ENSG00000171236; HGNC ID: 29480
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region12223515
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space16502470
GO:0016020NAS-membrane3856868
GO:0035580TAS-specific granule lumen-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome23376485
GO:1904724TAS-tertiary granule lumen-
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO:0005160IEA-transforming growth factor beta receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0001938IEA-positive regulation of endothelial cell proliferation-
GO:0008150ND-biological_process-
GO:0030511IEA-positive regulation of transforming growth factor beta receptor signaling pathway-
GO:0043312TAS-neutrophil degranulation-
GO:0045766IEA-positive regulation of angiogenesis-
GO:0050873IEA-brown fat cell differentiation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1924155
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018