AutismKB 2.0

Annotation Details for AGAP2


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Basic Information Top
Gene Symbol:AGAP2 ( CENTG1,FLJ16430,GGAP2,KIAA0167,PIKE )
Gene Full Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Band: 12q14.1
Quick LinksEntrez ID:116986; OMIM: 605476; Uniprot ID:AGAP2_HUMAN; ENSEMBL ID: ENSG00000135439; HGNC ID: 16921
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005634ISS-nucleus11136977
GO:0005730IDA-nucleolus-
GO:0005739IDA-mitochondrion-
GO:0016020IDA-membrane19946888
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0003924IEA-GTPase activity-
GO:0005096IEA-GTPase activator activity-
GO:0005515IPI-protein binding21720388
GO:0005525IEA-GTP binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0015031IEA-protein transport-
GO:0042177IDA-negative regulation of protein catabolic process18374643
GO:0043524IGI-negative regulation of neuron apoptotic process18374643
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AGAP2EPB41L110835011136977 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AGAP2EPB41L112554911136977 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
AGAP2NF211084417891137 Reconstituted Complex
AGAP2NF212554917891137 Reconstituted Complex
AGAP2PIK3R111131311136977 Affinity Capture-Western; Reconstituted Complex
AGAP2PIK3R112554911136977 Affinity Capture-Western; Reconstituted Complex
AGAP2HOMER111484514528310 Affinity Capture-Western; Reconstituted Complex
AGAP2HOMER112554914528310 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data