AutismKB 2.0

Annotation Details for MRGPRX2


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Basic Information Top
Gene Symbol:MRGPRX2 ( MRGX2 )
Gene Full Name: MAS-related GPR, member X2
Band: 11p15.1
Quick LinksEntrez ID:117194; OMIM: 607228; Uniprot ID:MRGX2_HUMAN; ENSEMBL ID: ENSG00000183695; HGNC ID: 17983
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IEA-plasma membrane-
GO:0016021IC-integral component of membrane12915402
GO:0042629IEA-mast cell granule-
GO ID Evidence Qualifier GO_term References
GO:0004930IDA-G-protein coupled receptor activity12915402
GO:0042923IPI-neuropeptide binding12915402
GO:1990595ISS-mast cell secretagogue receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0019233NAS-sensory perception of pain12915402
GO:0030431NAS-sleep12915402
GO:0032467IMP-positive regulation of cytokinesis22888021
GO:0043303IDA-mast cell degranulation22069323
GO:0045576IDA-mast cell activation25517090
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3033115
  • Data Attributes: HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018