AutismKB 2.0

Annotation Details for TPH2


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Basic Information Top
Gene Symbol:TPH2 ( ADHD7,FLJ37295,MGC138871,MGC138872,NTPH )
Gene Full Name: tryptophan hydroxylase 2
Band: 12q21.1
Quick LinksEntrez ID:121278; OMIM: 607478; Uniprot ID:TPH2_HUMAN; ENSEMBL ID: ENSG00000139287; HGNC ID: 20692
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0043005IEA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0004510IEA-tryptophan 5-monooxygenase activity-
GO:0005506IEA-iron ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007623IEA-circadian rhythm-
GO:0009072IEA-aromatic amino acid family metabolic process-
GO:0014823IEA-response to activity-
GO:0031667IEA-response to nutrient levels-
GO:0042427IEA-serotonin biosynthetic process-
GO:0043627IEA-response to estrogen-
GO:0046219TAS-indolalkylamine biosynthetic process-
GO:0051384IEA-response to glucocorticoid-
GO:0051592IEA-response to calcium ion-
GO:0055114IEA-oxidation-reduction process-
GO:0071285IEA-cellular response to lithium ion-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
TPH2rs11178997, rs11178998, rs11178999, rs11179044, rs11179064, rs1386491, rs1386493, rs1386494, rs1386498, rs1487278, rs1487279, rs17110747, rs41313475, rs4290270, rs4570625, rs6582071, rs7305115 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:2651811
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040624-4'