AutismKB 2.0

Annotation Details for CLTC


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Basic Information Top
Gene Symbol:CLTC ( CHC,CHC17,CLH-17,CLTCL2,Hc,KIAA0034 )
Gene Full Name: clathrin, heavy chain (Hc)
Band: 17q23.1
Quick LinksEntrez ID:1213; OMIM: 118955; Uniprot ID:CLH1_HUMAN; ENSEMBL ID: ENSG00000141367; HGNC ID: 2092
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005764IDA-lysosome-
GO:0005768IDA-endosome-
GO:0005819IDA-spindle15858577
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane16210410
GO:0030118IMP-clathrin coat11756460
GO:0030118NAS-clathrin coat1765375
GO:0030130IEA-clathrin coat of trans-Golgi network vesicle-
GO:0030132IEA-clathrin coat of coated pit-
GO:0030136IDA-clathrin-coated vesicle19478182
GO:0030669TAS-clathrin-coated endocytic vesicle membrane-
GO:0031012IDA-extracellular matrix23979707
GO:0032588TAS-trans-Golgi network membrane-
GO:0036020TAS-endolysosome membrane-
GO:0042470IEA-melanosome-
GO:0043234IDA-protein complex21266579
GO:0070062IDA-extracellular exosome12519789
GO:0071439IDA-clathrin complex4066749
GO:1903561IDA-extracellular vesicle24769233
GO:1990498IDA-mitotic spindle microtubule21297582
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22681889
GO:0003725IDA-double-stranded RNA binding21266579
GO:0005198NAS-structural molecule activity1765375
GO:0005515IPI-protein binding12429846
GO:0019901ISS-protein kinase binding-
GO:0032051IPI-clathrin light chain binding4066749
GO:0097718IPI-disordered domain specific binding11756460
GO ID Evidence Qualifier GO_term References
GO:0000278IMP-mitotic cell cycle15858577
GO:0001649IDA-osteoblast differentiation16210410
GO:0006886NAS-intracellular protein transport1765375
GO:0006898IMP-receptor-mediated endocytosis15858577
GO:0006914IEA-autophagy-
GO:0007018TAS-microtubule-based movement-
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0031623IMP-receptor internalization14985334
GO:0032802TAS-low-density lipoprotein particle receptor catabolic process-
GO:0033572IMP-transferrin transport14985334
GO:0034383TAS-low-density lipoprotein particle clearance-
GO:0042147IMP-retrograde transport, endosome to Golgi20065094
GO:0048268IMP-clathrin coat assembly11756460
GO:0051301IEA-cell division-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0060236IMP-regulation of mitotic spindle organization21297582
GO:0061024TAS-membrane organization-
GO:1900126IDA-negative regulation of hyaluronan biosynthetic process24251095
GO:1900126IMP-negative regulation of hyaluronan biosynthetic process23509262
GO:1903077IMP-negative regulation of protein localization to plasma membrane19581412
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CLTCAP2A21066709280305 Reconstituted Complex
CLTCAP2A21076239280305 Reconstituted Complex
CLTCAP1B11066719280305 Reconstituted Complex
CLTCAP1B11076239280305 Reconstituted Complex
CLTCAMPH1067709603201 Reconstituted Complex
CLTCAMPH1076239603201 Reconstituted Complex
VCLCLTC1132578276759 Reconstituted Complex
VCLCLTC1076238276759 Reconstituted Complex
AP3B2CLTC1137889545220 Reconstituted Complex
AP3B2CLTC1076239545220 Reconstituted Complex
PICALMCLTC11390210436022 Affinity Capture-Western; Reconstituted Complex
PICALMCLTC10762310436022 Affinity Capture-Western; Reconstituted Complex
KITCLTC11001510477727 Affinity Capture-Western
KITCLTC10762310477727 Affinity Capture-Western
EPN2CLTC10762310567358 Reconstituted Complex
EPN2CLTC11656910567358 Reconstituted Complex
EPN1CLTC11896510692452 Affinity Capture-Western
EPN1CLTC10762310692452 Affinity Capture-Western
TNK2CLTC10762311278436 Reconstituted Complex
TNK2CLTC11548511278436 Reconstituted Complex
GGA2CLTC10762311301005 Reconstituted Complex
GGA2CLTC11669711301005 Reconstituted Complex
GGA3CLTC10762311301005 Reconstituted Complex
GGA3CLTC11677511301005 Reconstituted Complex
GGA1CLTC10762311301005 Reconstituted Complex
GGA1CLTC11754011301005 Reconstituted Complex
EHD1CLTC10762311423532 Reconstituted Complex
EHD1CLTC11613811423532 Reconstituted Complex
HGSCLTC11459311532964 16716190 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HGSCLTC10762311532964 16716190 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
HIP1CLTC10762311532990 11604514 Affinity Capture-Western; Reconstituted Complex
HIP1CLTC10933911532990 11604514 Affinity Capture-Western; Reconstituted Complex
MAP3K10CLTC11044012105200 Affinity Capture-Western
MAP3K10CLTC10762312105200 Affinity Capture-Western
LDLRAP1CLTC10762312221107 Reconstituted Complex
LDLRAP1CLTC11756112221107 Reconstituted Complex
CLINT1CLTC11503812429846 Reconstituted Complex
CLINT1CLTC10762312429846 Reconstituted Complex
DNAJC6CLTC10762312732633 Reconstituted Complex
DNAJC6CLTC11516712732633 Reconstituted Complex
SNX9CLTC11953512952949 Affinity Capture-MS
SNX9CLTC10762312952949 Affinity Capture-MS
TOM1CLTC10762314563850 Affinity Capture-Western
TOM1CLTC11535414563850 Affinity Capture-Western
SNX5CLTC11802215133132 Two-hybrid
SNX5CLTC10762315133132 Two-hybrid
ARMCX3CLTC11961416169070 Two-hybrid
ARMCX3CLTC10762316169070 Two-hybrid
C10orf88CLTC12306416169070 Two-hybrid
C10orf88CLTC10762316169070 Two-hybrid
STAMCLTC11372216716190 Affinity Capture-Western
STAMCLTC10762316716190 Affinity Capture-Western
STAMBPCLTC10762316716190 Affinity Capture-Western; Co-localization
STAMBPCLTC11586316716190 Affinity Capture-Western; Co-localization
STAMBPL1CLTC12161416716190 Affinity Capture-Western; Co-localization
STAMBPL1CLTC10762316716190 Affinity Capture-Western; Co-localization
MCCCLTC11033317353931 Affinity Capture-MS
MCCCLTC10762317353931 Affinity Capture-MS
TFE3CLTC11288817353931 Affinity Capture-MS
TFE3CLTC10762317353931 Affinity Capture-MS
IKBKECLTC10762317353931 Affinity Capture-MS
IKBKECLTC11500017353931 Affinity Capture-MS
SNCACLTC10762318614564 Affinity Capture-Western
SNCACLTC11250618614564 Affinity Capture-Western
MAP1LC3ACLTC12413720562859 Affinity Capture-MS
MAP1LC3ACLTC10762320562859 Affinity Capture-MS
PRKACACLTC11155320936779 Two-hybrid
PRKACACLTC10762320936779 Two-hybrid
WNK1CLTC12240320936779 Two-hybrid
WNK1CLTC10762320936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2388633
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2299'