AutismKB 2.0

Annotation Details for CCR1


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Basic Information Top
Gene Symbol:CCR1 ( CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1 )
Gene Full Name: chemokine (C-C motif) receptor 1
Band: 3p21.31
Quick LinksEntrez ID:1230; OMIM: 601159; Uniprot ID:CCR1_HUMAN; ENSEMBL ID: ENSG00000163823; HGNC ID: 1602
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane10660125
GO:0005886IMP-plasma membrane15001559
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7505609
GO:0009897IDA-external side of plasma membrane10706735
GO ID Evidence Qualifier GO_term References
GO:0004435IDA-phosphatidylinositol phospholipase C activity10734056
GO:0004950IDA-chemokine receptor activity10660125
GO:0005515IPI-protein binding8699119
GO:0016493IDA-C-C chemokine receptor activity10734056
GO:0019957IPI-C-C chemokine binding7545673
GO:0035717IPI-chemokine (C-C motif) ligand 7 binding7545673
GO:0071791IPI-chemokine (C-C motif) ligand 5 binding7545673
GO ID Evidence Qualifier GO_term References
GO:0002407TAS-dendritic cell chemotaxis16621978
GO:0006816IDA-calcium ion transport10734056
GO:0006874IDA-cellular calcium ion homeostasis10734056
GO:0006887IDA-exocytosis10734056
GO:0006935NAS-chemotaxis15474493
GO:0006954IEA-inflammatory response-
GO:0006955IDA-immune response10734056
GO:0007155TAS-cell adhesion10910894
GO:0007166TAS-cell surface receptor signaling pathway10770925
GO:0007187TAS-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger7505609
GO:0007204IDA-positive regulation of cytosolic calcium ion concentration10734056
GO:0007267IDA-cell-cell signaling10734056
GO:0009611TAS-response to wounding7505609
GO:0010629IMP-negative regulation of gene expression21403648
GO:0019221NAS-cytokine-mediated signaling pathway15474493
GO:0030335IMP-positive regulation of cell migration24056371
GO:0030502IMP-negative regulation of bone mineralization21403648
GO:0045672IMP-positive regulation of osteoclast differentiation21403648
GO:0051928IDA-positive regulation of calcium ion transport15764707
GO:0070098IDA-chemokine-mediated signaling pathway21403648
GO:0070374IMP-positive regulation of ERK1 and ERK2 cascade21403648
GO:0090026IDA-positive regulation of monocyte chemotaxis18587271
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CCL7CCR11076358530354 Reconstituted Complex
CCL7CCR11122578530354 Reconstituted Complex
CCL23CCR11122719886417 Reconstituted Complex
CCL23CCR11076359886417 Reconstituted Complex
CCL5CCR110763511116158 11449371 Reconstituted Complex
CCL5CCR111225511116158 11449371 Reconstituted Complex
CCL3L1CCR110763511449371 Reconstituted Complex
CCL3L1CCR111225311449371 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104618
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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