Gene Symbol:	CCR5 ( CC-CKR-5,CCCKR5,CD195,CKR-5,CKR5,CMKBR5,FLJ78003,IDDM22 )
Gene Full Name:	chemokine (C-C motif) receptor 5
Band:	3p21.31
Quick Links	Entrez ID:1234; OMIM: 601373; Uniprot ID:CCR5_HUMAN; ENSEMBL ID: ENSG00000160791; HGNC ID: 1606
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005737	TAS	-	cytoplasm	10415069
GO:0005768	IDA	-	endosome	10679098
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	TAS	-	integral component of plasma membrane	10393923
GO:0009897	IDA	-	external side of plasma membrane	10679098
GO:0009986	IDA	-	cell surface	10521508

GO ID	Evidence	Qualifier	GO_term	References
GO:0001618	IEA	-	virus receptor activity	-
GO:0003779	IDA	-	actin binding	12421915
GO:0004435	TAS	-	phosphatidylinositol phospholipase C activity	8663314
GO:0004950	TAS	-	chemokine receptor activity	10201901
GO:0005515	IPI	-	protein binding	10816381
GO:0015026	TAS	-	coreceptor activity	10469138
GO:0016493	IDA	-	C-C chemokine receptor activity	11278962
GO:0016493	NAS	-	C-C chemokine receptor activity	8639485
GO:0019957	IPI	-	C-C chemokine binding	8699119
GO:0071791	IPI	-	chemokine (C-C motif) ligand 5 binding	8699119

GO ID	Evidence	Qualifier	GO_term	References
GO:0000165	IEP	-	MAPK cascade	12032188
GO:0002407	TAS	-	dendritic cell chemotaxis	16621978
GO:0006816	IDA	-	calcium ion transport	8699119
GO:0006935	TAS	-	chemotaxis	10741397
GO:0006954	IEA	-	inflammatory response	-
GO:0006955	IEA	-	immune response	-
GO:0006968	TAS	-	cellular defense response	10201901
GO:0007166	TAS	-	cell surface receptor signaling pathway	8639485
GO:0007186	IMP	-	G-protein coupled receptor signaling pathway	19523456
GO:0007204	TAS	-	positive regulation of cytosolic calcium ion concentration	10201901
GO:0007267	IDA	-	cell-cell signaling	10679098
GO:0014808	IDA	-	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	19523456
GO:0019064	TAS	-	fusion of virus membrane with host plasma membrane	-
GO:0019722	IDA	-	calcium-mediated signaling	10679098
GO:0023052	IEP	-	signaling	12032188
GO:0030260	TAS	-	entry into host cell	-
GO:0070098	IEA	-	chemokine-mediated signaling pathway	-
GO:0070723	IMP	-	response to cholesterol	19523456
GO:0071222	IEP	-	cellular response to lipopolysaccharide	10679098

Gene Symbol	Interactant	Interaction ID	References	Description
CCR5	AFP	106682	12176010	Affinity Capture-Western
CCR5	AFP	107639	12176010	Affinity Capture-Western
CCR5	ARRB1	107639	12065593	Reconstituted Complex
CCR5	ARRB1	106901	12065593	Reconstituted Complex
CCR5	CD4	107358	10816381	Affinity Capture-Western
CCR5	CD4	107639	10816381	Affinity Capture-Western
PTK2	CCR5	111719	10384144	Affinity Capture-Western
PTK2	CCR5	107639	10384144	Affinity Capture-Western
CCL5	CCR5	107639	11116158 11449371 14637022	Affinity Capture-Western; Reconstituted Complex
CCL5	CCR5	112255	11116158 11449371 14637022	Affinity Capture-Western; Reconstituted Complex
JAK2	CCR5	109920	11278738	Affinity Capture-Western
JAK2	CCR5	107639	11278738	Affinity Capture-Western
PIK3R2	CCR5	111314	11350939	Affinity Capture-Western
PIK3R2	CCR5	107639	11350939	Affinity Capture-Western
STAT3	CCR5	112651	11350939	Affinity Capture-Western
STAT3	CCR5	107639	11350939	Affinity Capture-Western
STAT5B	CCR5	112654	11350939	Affinity Capture-Western
STAT5B	CCR5	107639	11350939	Affinity Capture-Western
CCL3L1	CCR5	107639	11449371 11734558	Reconstituted Complex
CCL3L1	CCR5	112253	11449371 11734558	Reconstituted Complex
CCL3	CCR5	112252	11700073	Reconstituted Complex
CCL3	CCR5	107639	11700073	Reconstituted Complex
CXCR4	CCR5	113607	12429730	Reconstituted Complex
CXCR4	CCR5	107639	12429730	Reconstituted Complex

AutismKB 2.0

Annotation Details for CCR5