AutismKB 2.0

Annotation Details for ABCC2


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Basic Information Top
Gene Symbol:ABCC2 ( ABC30,CMOAT,DJS,KIAA1010,MRP2,cMRP )
Gene Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Band: 10q24.2
Quick LinksEntrez ID:1244; OMIM: 601107; Uniprot ID:MRP2_HUMAN; ENSEMBL ID: ENSG00000023839; HGNC ID: 53
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0009986IDA-cell surface17825285
GO:0016324IDA-apical plasma membrane11093739
GO:0031526IEA-brush border membrane-
GO:0046581IEA-intercellular canaliculus-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding17825285
GO:0005524IEA-ATP binding-
GO:0008514TAS-organic anion transmembrane transporter activity7559771
GO:0015127TAS-bilirubin transmembrane transporter activity-
GO:0019904IEA-protein domain specific binding-
GO:0042626TAS-ATPase activity, coupled to transmembrane movement of substances7559771
GO:0043225TAS-ATPase-coupled anion transmembrane transporter activity-
GO ID Evidence Qualifier GO_term References
GO:0006810TAS-transport7559771
GO:0006855IEA-drug transmembrane transport-
GO:0006979IEA-response to oxidative stress-
GO:0007565IEA-female pregnancy-
GO:0009408IEA-response to heat-
GO:0015694IEA-mercury ion transport-
GO:0015722IEA-canalicular bile acid transport-
GO:0015723IEA-bilirubin transport-
GO:0015732IEA-prostaglandin transport-
GO:0030644IEA-cellular chloride ion homeostasis-
GO:0031427IEA-response to methotrexate-
GO:0032870IBA-cellular response to hormone stimulus-
GO:0043627IEA-response to estrogen-
GO:0046685IEA-response to arsenic-containing substance-
GO:0055085TAS-transmembrane transport-
GO:0070327IEA-thyroid hormone transport-
GO:0071222IEA-cellular response to lipopolysaccharide-
GO:0071347IEA-cellular response to interleukin-1-
GO:0071354IEA-cellular response to interleukin-6-
GO:0071356IEA-cellular response to tumor necrosis factor-
GO:0071549IEA-cellular response to dexamethasone stimulus-
GO:0097327IEA-response to antineoplastic agent-
GO:0099133IEA-ATP hydrolysis coupled anion transmembrane transport-
GO:1901086IEA-benzylpenicillin metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDZK1ABCC211120010496535 Two-hybrid
PDZK1ABCC210764710496535 Two-hybrid
PDZD3ABCC212294012615054 Reconstituted Complex
PDZD3ABCC210764712615054 Reconstituted Complex
SLC9A3R1ABCC211476912615054 Reconstituted Complex
SLC9A3R1ABCC210764712615054 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ABCC2rs3740066 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:1352447
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1523'