AutismKB 2.0

Annotation Details for ADH4


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Basic Information Top
Gene Symbol:ADH4 ( ADH-2 )
Gene Full Name: alcohol dehydrogenase 4 (class II), pi polypeptide
Band: 4q23
Quick LinksEntrez ID:127; OMIM: 103740; Uniprot ID:ADH4_HUMAN; ENSEMBL ID: ENSG00000198099; HGNC ID: 252
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0003960ISS-NADPH:quinone reductase activity-
GO:0004022IDA-alcohol dehydrogenase (NAD) activity3466164
GO:0004024EXP-alcohol dehydrogenase activity, zinc-dependent9982
GO:0004024IDA-alcohol dehydrogenase activity, zinc-dependent10407146
GO:0004032IEA-alditol:NADP+ 1-oxidoreductase activity-
GO:0004745IDA-retinol dehydrogenase activity15369820
GO:0004745TAS-retinol dehydrogenase activity-
GO:0005503IDA-all-trans retinal binding15369820
GO:0008270IDA-zinc ion binding10407146
GO:0016620IDA-oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor3466164
GO:0019115IDA-benzaldehyde dehydrogenase activity3466164
GO:0019841IDA-retinol binding10407146
GO:0035276IEA-ethanol binding-
GO:0051287IDA-NAD binding10407146
GO ID Evidence Qualifier GO_term References
GO:0001523IDA-retinoid metabolic process15369820
GO:0006066IDA-alcohol metabolic process3466164
GO:0006069IDA-ethanol oxidation16787387
GO:0006069TAS-ethanol oxidation-
GO:0006081IDA-cellular aldehyde metabolic process3466164
GO:0042572IDA-retinol metabolic process16787387
GO:0046164ISS-alcohol catabolic process-
GO:1901661ISS-quinone metabolic process-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
ADH4P1, P2, P3, P4, P6, rs1573496, rs971074 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:1349472
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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