AutismKB 2.0

Annotation Details for IQGAP3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IQGAP3 ( MGC10170,MGC10831,MGC1947 )
Gene Full Name: IQ motif containing GTPase activating protein 3
Band: 1q22
Quick LinksEntrez ID:128239; OMIM: NA; Uniprot ID:IQGA3_HUMAN; ENSEMBL ID: ENSG00000183856; HGNC ID: 20669
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005911IEA-cell-cell junction-
GO:0016328IEA-lateral plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005516IEA-calmodulin binding-
GO:0017048IEA-Rho GTPase binding-
GO:0070856IPI-myosin VI light chain binding21299499
GO ID Evidence Qualifier GO_term References
GO:0000082IEA-G1/S transition of mitotic cell cycle-
GO:0000187IEA-activation of MAPK activity-
GO:0007265IEA-Ras protein signal transduction-
GO:0008361IEA-regulation of cell size-
GO:0010628IEA-positive regulation of gene expression-
GO:0010629IEA-negative regulation of gene expression-
GO:0033601IEA-positive regulation of mammary gland epithelial cell proliferation-
GO:0043087IEA-regulation of GTPase activity-
GO:0070371IEA-ERK1 and ERK2 cascade-
GO:0071310IEA-cellular response to organic substance-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3028642
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018