AutismKB 2.0

Annotation Details for ADM


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Basic Information Top
Gene Symbol:ADM ( AM )
Gene Full Name: adrenomedullin
Band: 11p15.4
Quick LinksEntrez ID:133; OMIM: 103275; Uniprot ID:ADML_HUMAN; ENSEMBL ID: ENSG00000148926; HGNC ID: 259
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space12379507
GO:0005737IDA-cytoplasm12379507
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding8074714
GO:0005179IEA-hormone activity-
GO:0005515IPI-protein binding20074556
GO:0031700IEA-adrenomedullin receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0001570IDA-vasculogenesis16964401
GO:0001666IEA-response to hypoxia-
GO:0001843IEA-neural tube closure-
GO:0002026IEA-regulation of the force of heart contraction-
GO:0002031IDA-G-protein coupled receptor internalization10882736
GO:0006171IDA-cAMP biosynthetic process20074556
GO:0006701TAS-progesterone biosynthetic process10822232
GO:0007165TAS-signal transduction10822232
GO:0007204IEA-positive regulation of cytosolic calcium ion concentration-
GO:0007267TAS-cell-cell signaling8074714
GO:0007507IEA-heart development-
GO:0007565IEA-female pregnancy-
GO:0007568IEA-aging-
GO:0008015TAS-blood circulation8074714
GO:0008209IEA-androgen metabolic process-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0008285IEA-negative regulation of cell proliferation-
GO:0009409IEA-response to cold-
GO:0009611IEA-response to wounding-
GO:0010460IEA-positive regulation of heart rate-
GO:0019933IEA-cAMP-mediated signaling-
GO:0030819IDA-positive regulation of cAMP biosynthetic process10882736
GO:0031100IEA-animal organ regeneration-
GO:0031102IEA-neuron projection regeneration-
GO:0031623IDA-receptor internalization10882736
GO:0032496IEA-response to lipopolysaccharide-
GO:0032868IEA-response to insulin-
GO:0042475IEA-odontogenesis of dentin-containing tooth-
GO:0042594IEA-response to starvation-
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043116IEA-negative regulation of vascular permeability-
GO:0045766IEA-positive regulation of angiogenesis-
GO:0045906IDA-negative regulation of vasoconstriction11410113
GO:0046879IEA-hormone secretion-
GO:0048589IEA-developmental growth-
GO:0051384IEA-response to glucocorticoid-
GO:0060670IEA-branching involved in labyrinthine layer morphogenesis-
GO:0060712IEA-spongiotrophoblast layer development-
GO:0097084IEA-vascular smooth muscle cell development-
GO:2001214IEA-positive regulation of vasculogenesis-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108058
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018