AutismKB 2.0

Annotation Details for ADORA2B


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Basic Information Top
Gene Symbol:ADORA2B ( ADORA2 )
Gene Full Name: adenosine A2b receptor
Band: 17p12
Quick LinksEntrez ID:136; OMIM: 600446; Uniprot ID:AA2BR_HUMAN; ENSEMBL ID: ENSG00000170425; HGNC ID: 264
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7558011
GO ID Evidence Qualifier GO_term References
GO:0001609IEA-G-protein coupled adenosine receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0000187TAS-activation of MAPK activity10101031
GO:0001973IEA-adenosine receptor signaling pathway-
GO:0002882IEA-positive regulation of chronic inflammatory response to non-antigenic stimulus-
GO:0006968TAS-cellular defense response10101031
GO:0007186TAS-G-protein coupled receptor signaling pathway7558011
GO:0007189IEA-adenylate cyclase-activating G-protein coupled receptor signaling pathway-
GO:0007190TAS-activation of adenylate cyclase activity8022409
GO:0007254TAS-JNK cascade10101031
GO:0007588TAS-excretion7836474
GO:0010575IEA-positive regulation of vascular endothelial growth factor production-
GO:0031284IEA-positive regulation of guanylate cyclase activity-
GO:0031668IEA-cellular response to extracellular stimulus-
GO:0032722IEA-positive regulation of chemokine production-
GO:0032755IEA-positive regulation of interleukin-6 production-
GO:0043306IEA-positive regulation of mast cell degranulation-
GO:0044267TAS-cellular protein metabolic process-
GO:0060087IEA-relaxation of vascular smooth muscle-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EZRADORA2B11327112080047 Affinity Capture-Western
EZRADORA2B10664812080047 Affinity Capture-Western
SLC9A3R2ADORA2B11475412080047 Affinity Capture-Western
SLC9A3R2ADORA2B10664812080047 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ADORA2Brs1076424 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:99403
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060511-1'