AutismKB 2.0

Annotation Details for CR2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CR2 ( C3DR,CD21,SLEB9 )
Gene Full Name: complement component (3d/Epstein Barr virus) receptor 2
Band: 1q32.2
Quick LinksEntrez ID:1380; OMIM: 120650; Uniprot ID:CR2_HUMAN; ENSEMBL ID: ENSG00000117322; HGNC ID: 2336
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016021NAS-integral component of membrane2827171
GO:0043235IDA-receptor complex23382219
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0001618IEA-virus receptor activity-
GO:0001848IDA-complement binding11034390
GO:0003677IDA-DNA binding22885687
GO:0004875NAS-complement receptor activity2827171
GO:0004888NAS-transmembrane signaling receptor activity2827171
GO:0042803IDA-protein homodimerization activity11728339
GO ID Evidence Qualifier GO_term References
GO:0002430IEA-complement receptor mediated signaling pathway-
GO:0006955NAS-immune response2827171
GO:0006958IEA-complement activation, classical pathway-
GO:0030183IDA-B cell differentiation2995485
GO:0030449TAS-regulation of complement activation-
GO:0042100IDA-B cell proliferation2995485
GO:0045087IEA-innate immune response-
GO:0046718IEA-viral entry into host cell-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CR2ANXA61077711831222 Reconstituted Complex
CR2ANXA61068061831222 Reconstituted Complex
CR2CD191077711383329 9804823 Affinity Capture-Western
CR2CD191073681383329 9804823 Affinity Capture-Western
CR2CD811077711383329 Affinity Capture-Western
CR2CD811074131383329 Affinity Capture-Western
CR2CR11077691708808 Affinity Capture-Western
CR2CR11077711708808 Affinity Capture-Western
IFITM1CR21140911383329 Affinity Capture-Western
IFITM1CR21077711383329 Affinity Capture-Western
IFNA1CR21077711849076 Reconstituted Complex
IFNA1CR21096621849076 Reconstituted Complex
FCER2CR21077717515913 Reconstituted Complex
FCER2CR21085027515913 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CR2rs1048971, rs3767933 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88489
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved