AutismKB 2.0

Annotation Details for CRHR1


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Basic Information Top
Gene Symbol:CRHR1 ( CRF-R,CRF1,CRFR1,CRH-R1h,CRHR,CRHR1L,CRHR1f )
Gene Full Name: corticotropin releasing hormone receptor 1
Band: 17q21.31
Quick LinksEntrez ID:1394; OMIM: 122561; Uniprot ID:CRFR1_HUMAN; ENSEMBL ID: ENSG00000120088; HGNC ID: 2357
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005768IEA-endosome-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane10598591
GO:0016021IDA-integral component of membrane23863939
GO:0031226IDA-intrinsic component of plasma membrane18292205
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding18801728
GO:0015056IDA-corticotrophin-releasing factor receptor activity18292205
GO ID Evidence Qualifier GO_term References
GO:0006955TAS-immune response7692441
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0007190TAS-activation of adenylate cyclase activity10598591
GO:0007565NAS-female pregnancy7585095
GO:0007567TAS-parturition10598591
GO:0010578IMP-regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway23863939
GO:0010579IDA-positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway18292205
GO:0051458ISS-corticotropin secretion-
GO:0071376IDA-cellular response to corticotropin-releasing hormone stimulus18292205
GO:1901386IDA-negative regulation of voltage-gated calcium channel activity18292205
GO:2000852ISS-regulation of corticosterone secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CRHR1CRH1077829423932 10598591 Reconstituted Complex
CRHR1CRH1077849423932 10598591 Reconstituted Complex
UCNCRHR11131968612563 9423932 Reconstituted Complex
UCNCRHR11077848612563 9423932 Reconstituted Complex
GNAI1CRHR110903210598591 Affinity Capture-Western
GNAI1CRHR110778410598591 Affinity Capture-Western
GNAO1CRHR110903710598591 Affinity Capture-Western
GNAO1CRHR110778410598591 Affinity Capture-Western
GNAQCRHR110903810598591 Affinity Capture-Western
GNAQCRHR110778410598591 Affinity Capture-Western
GNASCRHR110904010598591 Affinity Capture-Western
GNASCRHR110778410598591 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CRHR1rs110402, rs16940665, rs16940674, rs171440, rs1724425, rs17689966, rs17762882, rs1876827, rs2316763, rs242925, rs242937 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88498
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081231-1'