AutismKB 2.0

Annotation Details for CRY1


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Basic Information Top
Gene Symbol:CRY1 ( PHLL1 )
Gene Full Name: cryptochrome 1 (photolyase-like)
Band: 12q23.3
Quick LinksEntrez ID:1407; OMIM: 601933; Uniprot ID:CRY1_HUMAN; ENSEMBL ID: ENSG00000008405; HGNC ID: 2384
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634ISS-nucleus-
GO:0005739IEA-mitochondrion-
GO ID Evidence Qualifier GO_term References
GO:0000166IEA-nucleotide binding-
GO:0000989IDA-transcription factor activity, transcription factor binding15147242
GO:0001046IEA-core promoter sequence-specific DNA binding-
GO:0001047ISS-core promoter binding-
GO:0003677TAS-DNA binding9801304
GO:0003690IDA-double-stranded DNA binding9801304
GO:0003904IDANOTdeoxyribodipyrimidine photo-lyase activity8909283
GO:0003914IDANOTDNA (6-4) photolyase activity8909283
GO:0005515IPI-protein binding9383998
GO:0008134IEA-transcription factor binding-
GO:0009882NAS-blue light photoreceptor activity8909283
GO:0019901IEA-protein kinase binding-
GO:0019902IPI-phosphatase binding9383998
GO:0035257IPI-nuclear hormone receptor binding22170608
GO:0042826IEA-histone deacetylase binding-
GO:0043130ISS-ubiquitin binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter12397359
GO:0006094ISS-gluconeogenesis-
GO:0006351IEA-transcription, DNA-templated-
GO:0006975ISS-DNA damage induced protein phosphorylation-
GO:0009785NAS-blue light signaling pathway8909283
GO:0018298IEA-protein-chromophore linkage-
GO:0019915IEA-lipid storage-
GO:0031397ISS-negative regulation of protein ubiquitination-
GO:0032868IEA-response to insulin-
GO:0032922ISS-circadian regulation of gene expression-
GO:0033762ISS-response to glucagon-
GO:0042593ISS-glucose homeostasis-
GO:0042752ISS-regulation of circadian rhythm-
GO:0042754ISS-negative regulation of circadian rhythm-
GO:0043153ISS-entrainment of circadian clock by photoperiod-
GO:0045744ISS-negative regulation of G-protein coupled receptor protein signaling pathway-
GO:0045892IDA-negative regulation of transcription, DNA-templated12397359
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:2000001ISS-regulation of DNA damage checkpoint-
GO:2000323ISS-negative regulation of glucocorticoid receptor signaling pathway-
GO:2000850IEA-negative regulation of glucocorticoid secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CRY1ARNTL10779710531061 Two-hybrid
CRY1ARNTL10689910531061 Two-hybrid
CRY1CBLB10779716189514 Two-hybrid
CRY1CBLB10731616189514 Two-hybrid
PER2CRY110779710531061 11533252 Affinity Capture-Western; Two-hybrid
PER2CRY111438710531061 11533252 Affinity Capture-Western; Two-hybrid
PER1CRY111121010531061 Two-hybrid
PER1CRY110779710531061 Two-hybrid
MDFICRY110779716189514 Two-hybrid
MDFICRY111035316189514 Two-hybrid
PLSCR1CRY110779716189514 Two-hybrid
PLSCR1CRY111137316189514 Two-hybrid
TRAF2CRY111303816189514 Two-hybrid
TRAF2CRY110779716189514 Two-hybrid
KRTAP4-12CRY110779716189514 Two-hybrid
KRTAP4-12CRY112375616189514 Two-hybrid
CRY1CRY110779717073458 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1270841
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010426-2'