AutismKB 2.0

Annotation Details for SMCR8


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Basic Information Top
Gene Symbol:SMCR8 ( FLJ34716,FLJ60657 )
Gene Full Name: Smith-Magenis syndrome chromosome region, candidate 8
Band: 17p11.2
Quick LinksEntrez ID:140775; OMIM: NA; Uniprot ID:SMCR8_HUMAN; ENSEMBL ID: ENSG00000176994; HGNC ID: 17921
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000785IDA-chromatin28195531
GO:0005654IDA-nucleoplasm28195531
GO:0005737IDA-cytoplasm27193190
GO:0032045IDA-guanyl-nucleotide exchange factor complex27103069
GO:1990316IDA-ATG1/ULK1 kinase complex28195531
GO:1990316IDAcolocalizes_withATG1/ULK1 kinase complex27193190
GO ID Evidence Qualifier GO_term References
GO:0004860IMP-protein kinase inhibitor activity28195531
GO:0005515IPI-protein binding27103069
GO:0017112IDAcontributes_toRab guanyl-nucleotide exchange factor activity27103069
GO:0019901IPI-protein kinase binding27103069
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006469IMP-negative regulation of protein kinase activity28195531
GO:0006914IEA-autophagy-
GO:0010506IMP-regulation of autophagy27103069
GO:0010629IMP-negative regulation of gene expression28195531
GO:0016242IMP-negative regulation of macroautophagy28195531
GO:0032008IMP-positive regulation of TOR signaling28195531
GO:0043547IEA-positive regulation of GTPase activity-
GO:1901098IMP-positive regulation of autophagosome maturation28195531
GO:1902902IMP-negative regulation of autophagosome assembly28195531
GO:1903432IMP-regulation of TORC1 signaling27559131
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMCR8RB1CC112670420562859 Affinity Capture-MS
SMCR8RB1CC111516020562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444720
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061122-1'