AutismKB 2.0

Annotation Details for CSF2RB


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Basic Information Top
Gene Symbol:CSF2RB ( CD131,CDw131,IL3RB,IL5RB )
Gene Full Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Band: 22q12.3
Quick LinksEntrez ID:1439; OMIM: 138981; Uniprot ID:IL3RB_HUMAN; ENSEMBL ID: ENSG00000100368; HGNC ID: 2436
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887NAS-integral component of plasma membrane1702217
GO:0030526TAS-granulocyte macrophage colony-stimulating factor receptor complex9410898
GO ID Evidence Qualifier GO_term References
GO:0004713TAS-protein tyrosine kinase activity-
GO:0004872TAS-receptor activity9410898
GO:0004912TAScontributes_tointerleukin-3 receptor activity9410898
GO:0004914TAScontributes_tointerleukin-5 receptor activity9410898
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding1495999
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0007165NAS-signal transduction1702217
GO:0007585TAS-respiratory gaseous exchange9410898
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0032496IEA-response to lipopolysaccharide-
GO:0036016IEA-cellular response to interleukin-3-
GO:0038043IEA-interleukin-5-mediated signaling pathway-
GO:0038156IEA-interleukin-3-mediated signaling pathway-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0044267TAS-cellular protein metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
JAK2CSF2RB1078267527392 7775438 Affinity Capture-Western; Reconstituted Complex
JAK2CSF2RB1099207527392 7775438 Affinity Capture-Western; Reconstituted Complex
LYNCSF2RB1078267636265 9973406 Affinity Capture-Western; Protein-peptide
LYNCSF2RB1102457636265 9973406 Affinity Capture-Western; Protein-peptide
PTPN6CSF2RB1078268246974 9162089 Affinity Capture-Western; Reconstituted Complex
PTPN6CSF2RB1117428246974 9162089 Affinity Capture-Western; Reconstituted Complex
IL3CSF2RB1078268649415 Reconstituted Complex
IL3CSF2RB1097778649415 Reconstituted Complex
PTPN11CSF2RB1078269162089 Affinity Capture-Western; Reconstituted Complex
PTPN11CSF2RB1117459162089 Affinity Capture-Western; Reconstituted Complex
IL5RACSF2RB1078269516124 Affinity Capture-Western
IL5RACSF2RB1097829516124 Affinity Capture-Western
YWHAZCSF2RB10782610477722 Affinity Capture-Western; Reconstituted Complex
YWHAZCSF2RB11336610477722 Affinity Capture-Western; Reconstituted Complex
PRKCBCSF2RB10782610490850 Affinity Capture-Western
PRKCBCSF2RB11156510490850 Affinity Capture-Western
GNB2L1CSF2RB10782610490850 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GNB2L1CSF2RB11567110490850 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SHC1CSF2RB10782610704825 Affinity Capture-Western
SHC1CSF2RB11236110704825 Affinity Capture-Western
CSF2RBCSF2RB10782611207369 Co-crystal Structure
MAD2L1CSF2RB10782611551900 Affinity Capture-Western; Reconstituted Complex
MAD2L1CSF2RB11026011551900 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
CSF2RBrs11705394, rs131840, rs131842, rs17811365, rs2072707, rs2075936, rs2075942, rs2284031, rs7285064, rs909486 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1339759
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080115-1'