AutismKB 2.0

Annotation Details for E2F7


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Basic Information Top
Gene Symbol:E2F7 ( FLJ12981 )
Gene Full Name: E2F transcription factor 7
Band: 12q21.2
Quick LinksEntrez ID:144455; OMIM: 612046; Uniprot ID:E2F7_HUMAN; ENSEMBL ID: ENSG00000165891; HGNC ID: 23820
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0016607IDA-nuclear speck-
GO ID Evidence Qualifier GO_term References
GO:0000977IEA-RNA polymerase II regulatory region sequence-specific DNA binding-
GO:0001047IDA-core promoter binding22903062
GO:0001227IEA-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding22802528
GO:0003700IMP-transcription factor activity, sequence-specific DNA binding22903062
GO:0003714ISS-transcription corepressor activity-
GO:0005515IPI-protein binding18202719
GO:0042802IPI-identical protein binding15133492
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter22802528
GO:0001890ISS-placenta development-
GO:0002040IMP-sprouting angiogenesis22903062
GO:0006351IEA-transcription, DNA-templated-
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0008285IMP-negative regulation of cell proliferation22802528
GO:0030330IDA-DNA damage response, signal transduction by p53 class mediator22802528
GO:0032466ISS-negative regulation of cytokinesis-
GO:0032877ISS-positive regulation of DNA endoreduplication-
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter22903062
GO:0060707ISS-trophoblast giant cell differentiation-
GO:0060718ISS-chorionic trophoblast cell differentiation-
GO:0070365ISS-hepatocyte differentiation-
GO:0071930IDA-negative regulation of transcription involved in G1/S transition of mitotic cell cycle22802528
GO:2000134ISS-negative regulation of G1/S transition of mitotic cell cycle-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
E2F7RUVBL112685517353931 Affinity Capture-MS
E2F7RUVBL111416617353931 Affinity Capture-MS
E2F7E2F712685514633988 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1289147
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3527'